Over 77 million dogs and 93 million cats share our households in the United States. Multiple
studies have demonstrated the importance of pets in their owners' physical and mental …

Leishmaniasis is a vector-borne neglected tropical disease associated with a spectrum of
clinical manifestations, ranging from self-healing cutaneous lesions to fatal visceral …

Visceral leishmaniases are vector-borne parasitic diseases caused by protozoa belonging
to the genus Leishmania. The heterogeneity of clinical manifestations and epidemiological …

To identify susceptibility loci for visceral leishmaniasis, we undertook genome-wide
association studies in two populations: 989 cases and 1,089 controls from India and 357 …

Due to their chemical versatility, transition metals were incorporated as cofactors for several
basic metabolic pathways in living organisms. This same characteristic makes them …

Host genetic factors play a crucial role in immune response. To determine whether the
differences between C57Bl/6 and BALB-C mice are due only to the production of cytokines …

The infectious metacyclic promastigotes of Leishmania protozoa establish infection in a
mammalian host after they are deposited into the dermis by a sand fly vector. Several …

Visceral leishmaniasis (VL), also known as dumdum fever or kala-azar, is characterized by
intermittent fever, substantial weight loss, hepatosplenomegaly and pancytopenia. If left …

To test the validity of the polymerase chain reaction for diagnosing American visceral
leishmaniasis, 88 suspected cases were studied. Diagnosis was confirmed in 47 (53.5%) …

Leishmaniasis is a neglected tropical disease caused by Leishmania protozoa and
transmitted by a sand fly vector. There are three main disease manifestations: self-healing …