In-peptide synthesis of di-oxazolidinone and dehydroamino acid–oxazolidinone motifs as β-turn inducers
R De Marco, A Greco, S Rupiani, A Tolomelli… - Organic & …, 2013 - pubs.rsc.org
Small and easy-to-do mimetics of β-turns are of great interest to interfere with protein–
protein recognition events mediated by β-turn recognition motifs. We propose a …
protein recognition events mediated by β-turn recognition motifs. We propose a …
Structural and Biological Exploration of Phe3–Phe4-Modified Endomorphin-2 Peptidomimetics
G Lesma, S Salvadori, F Airaghi… - ACS Medicinal …, 2013 - ACS Publications
This study reports on our ongoing investigation on hybrid EM-2 analogues, in which the
great potential of β-amino acids was exploited to generate multiple conformational …
great potential of β-amino acids was exploited to generate multiple conformational …
Synthesis, pharmacological evaluation and conformational investigation of endomorphin-2 hybrid analogues
G Lesma, S Salvadori, F Airaghi, E Bojnik, A Borsodi… - Molecular …, 2013 - Springer
This study reports on new pharmacologically active endomorphin-2 analogues,
incorporating β 2-hPhe, β 3-hPhe and β 3-hTic unnatural amino acids in the place of the Phe …
incorporating β 2-hPhe, β 3-hPhe and β 3-hTic unnatural amino acids in the place of the Phe …