New insights into the role of sequestosome 1/p62 mutant proteins in the pathogenesis of Paget's disease of bone

SL Rea, JP Walsh, R Layfield, T Ratajczak… - Endocrine …, 2013 - academic.oup.com
Paget's disease of bone (PDB) is characterized by focal areas of aberrant and excessive
bone turnover, specifically increased bone resorption and disorganized bone formation …

P97/CDC-48: proteostasis control in tumor cell biology

D Fessart, E Marza, S Taouji, F Delom, E Chevet - Cancer letters, 2013 - Elsevier
Abstract P97/CDC-48 is a prominent member of a highly evolutionary conserved Walker
cassette–containing AAA+ ATPases. It has been involved in numerous cellular processes …

[HTML][HTML] Suppression of urinary bladder urothelial carcinoma cell by the ethanol extract of pomegranate fruit through cell cycle arrest and apoptosis

ST Lee, MH Lu, LH Chien, TF Wu, LC Huang… - … and alternative medicine, 2013 - Springer
Background Pomegranate possesses many medicinal properties such as antioxidant, anti-
inflammation and antitumor. It has been extensively used as a folk medicine by many …

The valosin-containing protein promotes cardiac survival through the inducible isoform of nitric oxide synthase

P Lizano, E Rashed, H Kang, H Dai, X Sui… - Cardiovascular …, 2013 - academic.oup.com
Aims Expression of the heat shock protein 22 (Hsp22) in the heart stimulates cardiac cell
survival through activation of the Akt pathway and expression of the inducible nitric oxide …

Disruption of neurogenesis by hypothalamic inflammation in obesity or aging

S Purkayastha, D Cai - Reviews in Endocrine and Metabolic Disorders, 2013 - Springer
Adult neural stem cells contribute to neurogenesis and plasticity of the brain which is
essential for central regulation of systemic homeostasis. Damage to these homeostatic …

Roles of Cdc48 in regulated protein degradation in yeast

A Buchberger - Regulated proteolysis in microorganisms, 2013 - Springer
The chaperone-related, ubiquitin-selective AAA (ATPase associated with a variety of cellular
activities) protein Cdc48 (also known as TER94, p97 and VCP) is a key regulator of …

Functional proteomics reveals the protective effects of saffron ethanolic extract on hepatic ischemia‐reperfusion injury

TL Pan, TH Wu, PW Wang, YL Leu, N Sintupisut… - …, 2013 - Wiley Online Library
Hepatic ischemia‐reperfusion (IR) injury is a common clinical problem and ROS may be a
contributing factor on IR injury. The current study evaluates the potential protective effect of …

Neuroinflammation in overnutrition-induced diseases

D Cai - Vitamins & Hormones, 2013 - Elsevier
Inflammation is a biological response mounted by the immune system against dangerous
assaults that threaten the integrity and normal physiology of an organism. During the past …

Methyltransferases and uses thereof

PO FALNES, S KERNSTOCK, A Klungland, M FUSSER - 2013 - Google Patents
G01N33/5008—Chemical analysis of biological material, eg blood, urine; Testing involving
biospecific ligand binding methods; Immunological testing involving human or animal cells …

[引用][C] Kemik paget hastalığı ve frontotemporal demans ile gözlenen inklüzyon cisimcik miyopati hastalığıyla (IBMPFD) ilişkili bazı vcp mutant proteinlerin rekombinant …

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يتم تحضير الملف الاستخدام المجاني إذا كنت ترغب في الوصول الكامل إلى هذا المحتوى وقاعدة …