Monoclonal antibody G250 (mAbG250) recognizes a determinant on carbonic anhydrase IX
(CAIX). CAIX is expressed by virtually all renal cell carcinomas of the clear cell type …

Angiogenesis, the development of new vessels from existing vasculature, plays a central
role in tumor growth, survival, and progression. On the molecular level it is controlled by a …

Abstract The International Society of Urological Pathology convened a consensus
conference on renal cancer, preceded by an online survey, to address issues relating to the …

Carbonic anhydrase IX (CA IX) is regarded as one of the most prominent markers of tumor
hypoxia with potential to serve as a diagnostic biomarker, prognostic indicator as well as …

Objective Retrospective data analyses have suggested that carbonic anhydrase IX (CAIX)
may have a predictive role in patients with metastatic clear cell renal cell carcinoma (ccRCC) …

Objective To evaluate carbonic anhydrase IX (CAIX) expression as an independent
prognostic marker for clear cell renal cell carcinoma (ccRCC). With recent smaller studies …

Metastatic disease is responsible for the majority of cancer related deaths. Tumour-
associated carbonic anhydrase IX (CA IX) is a powerful marker to diagnose various types of …

BACKGROUND: In our 2007 retrospective study, we reported that single nucleotide
polymorphisms (SNPs) in the signal transducer and activator of transcription 3 (acute-phase …

As our understanding of the molecular events leading to the development and progression
of genitourologic malignancies, new markers of detection, prognostication, and therapy …

Agents targeting the immune system have been a historical standard of care in metastatic
renal cell carcinoma (RCC), but have largely been supplanted by newer targeted therapy …