Metformin is the most commonly prescribed antidiabetic oral agent. It has also been used off-
label for polycystic ovarian syndrome, steatohepatitis, and HIV-associated metabolic …

Endoplasmic reticulum (ER) stress generally occurs in secretory cell types. It has been
reported that Leydig cells, which produce testosterone in response to human chorionic …

The current epidemic of obesity and type 2 diabetes is attributed to a high carbohydrate diet,
containing mainly high fructose corn syrup and sucrose. More than two thirds of diabetic …

Immunometabolism investigates the multiple links between the immune system and
metabolism. One main focus of immunometabolism investigates how obesity impacts the …

Many of the most commonly used drugs precede techniques for target identification and
drug specificity and were developed on the basis of efficacy and safety, an approach …

Gprotein coupled receptors (GPCRs) constitute the largest family of receptors in the human
genome with more than 700 members divided into 5 subfamilies based on similarities of …

Psychiatry disorders are creating its own place in morbidity now a days. Various factors like
cost of drugs, local paradigms, etc, plays a critical role for selecting the appropriate therapy …

Despite the decreased mortality rates attributable to breast cancer in women, the number of
cases diagnosed has steadily increased over the past 30 years. This is believed to be due …

In 2008 the global prevalence of hypertension [high blood pressure (BP), systolic≥ 140
mmHg and/or diastolic≥ 90 mmHg] was around 40% in adults> 25 yrs of age, according to …