The gastrointestinal tract is lined by a series of epithelia that share functional requirements
but also have distinct, highly specialized roles. Distinct populations of somatic stem cells …

The acquisition of flight contributed to the success of insects and winged forms are present
in most orders. Key to understanding the origin of wings will be knowledge of the earliest …

The Drosophila ovarian germline stem cells (GSCs) constantly experience self-renewal and
differentiation, ensuring the female fertility throughout life. The balance between GSC self …

Maintenance of adult stem cells is largely dependent on the balance between their self-
renewal and differentiation. The Drosophila ovarian germline stem cells (GSCs) provide a …

Abstract According to the World Health Organization, a fertile man typically has a sperm
count of 15 million per milliliter of semen. This spermatogenic capacity is determined by …

Germline stem cells (GSCs) produce gametes throughout the reproductive life of many
animals, and intensive studies have revealed critical roles of BMP signaling to maintain GSC …

Smad 蛋白家族是转化生长因子-β (transforminggrowthfactor—β, TGF—β)
超家族下游最重要的细胞内信号传导蛋白, 在调节细胞增殖, 分化, 迁移, 凋亡中具有重要作用 …

ETS family transcription factors are evolutionarily conserved downstream effectors of
Ras/MAPK signaling with critical roles in development and cancer. In Drosophila, the ETS …

Bone morphogenetic proteins (BMPs) signaling essentially regulates a wide range of
biological responses. Although multiple regulators at different layers of the receptor-effectors …

When cell cycle withdrawal accompanies terminal differentiation, biosynthesis and cellular
growth are likely to change also. In this study, nucleolus size was monitored during cell fate …