Treatment of infant leukemias: challenge and promise
P Brown - Hematology 2013, the American Society of …, 2013 - ashpublications.org
Leukemia in infants is rare but generates tremendous interest due to its aggressive clinical
presentation in a uniquely vulnerable host, its poor response to current therapies, and its …
presentation in a uniquely vulnerable host, its poor response to current therapies, and its …
Acute myeloid leukemia creates an arginase-dependent immunosuppressive microenvironment
F Mussai, C De Santo, I Abu-Dayyeh… - Blood, The Journal …, 2013 - ashpublications.org
Acute myeloid leukemia (AML) is the most common acute leukemia in adults and the second
most common frequent leukemia of childhood. Patients may present with lymphopenia or …
most common frequent leukemia of childhood. Patients may present with lymphopenia or …
Results of the AIEOP AML 2002/01 multicenter prospective trial for the treatment of children with acute myeloid leukemia
We evaluated the outcome of 482 children with acute myeloid leukemia (AML) enrolled in
the Associazione Italiana di Ematologia e Oncologia Pediatrica AML 2002/01 trial …
the Associazione Italiana di Ematologia e Oncologia Pediatrica AML 2002/01 trial …
NUP98/JARID1A is a novel recurrent abnormality in pediatric acute megakaryoblastic leukemia with a distinct HOX gene expression pattern
JDE de Rooij, IHIM Hollink, S Arentsen-Peters… - Leukemia, 2013 - nature.com
Cytogenetic abnormalities and early response to treatment are the main prognostic factors in
acute myeloid leukemia (AML). Recently, NUP98/NSD1 (t (5; 11)(q35; p15)), a …
acute myeloid leukemia (AML). Recently, NUP98/NSD1 (t (5; 11)(q35; p15)), a …
Excess treatment reduction including anthracyclines results in higher incidence of relapse in core binding factor acute myeloid leukemia in children
D Tomizawa, A Tawa, T Watanabe, AM Saito, K Kudo… - Leukemia, 2013 - nature.com
Patients with core binding factor acute myeloid leukemia (CBF-AML) with translocation (8;
21)(q22; q22)[t (8; 21)] and inversion of chromosome 16 (p13. 1q22), or its variant t (16; …
21)(q22; q22)[t (8; 21)] and inversion of chromosome 16 (p13. 1q22), or its variant t (16; …
Nutritional status and dietary intake of children with acute leukaemia during induction or consolidation chemotherapy
SY Tan, BK Poh, MH Nadrah… - Journal of Human …, 2013 - Wiley Online Library
Background The assessment of nutritional status among paediatric patients is important for
the planning and execution of nutritional strategies that strive to optimise the quality of life …
the planning and execution of nutritional strategies that strive to optimise the quality of life …
Appropriate dose reduction in induction therapy is essential for the treatment of infants with acute myeloid leukemia: a report from the Japanese Pediatric Leukemia …
D Tomizawa, A Tawa, T Watanabe, AM Saito… - International journal of …, 2013 - Springer
Abstract Infants (< 1 year old) with acute myeloid leukemia (AML) are particularly vulnerable
to intensive cytotoxic therapy. Indeed, the mortality rate was high among infants enrolled in …
to intensive cytotoxic therapy. Indeed, the mortality rate was high among infants enrolled in …
Outcome of adolescents and young adults with acute myeloid leukemia treated on COG trials compared to CALGB and SWOG trials
WG Woods, ARK Franklin, TA Alonzo, RB Gerbing… - Cancer, 2013 - Wiley Online Library
BACKGROUND A retrospective meta‐analysis of adolescents and young adults (AYAs) with
acute myeloid leukemia (AML) was performed to determine if differences in outcome exist …
acute myeloid leukemia (AML) was performed to determine if differences in outcome exist …
Use of zoledronic acid for treatment of chemotherapy related osteonecrosis in children and adolescents: a retrospective analysis
B Padhye, L Dalla‐Pozza, DG Little… - Pediatric blood & …, 2013 - Wiley Online Library
Background Osteonecrosis (ON) is a disabling complication of chemotherapy, especially
steroids in children and adolescents. There are few reports in the literature of non‐surgical …
steroids in children and adolescents. There are few reports in the literature of non‐surgical …
Pediatric relapsed or refractory leukemia: new pharmacotherapeutic developments and future directions
KJ August, A Narendran, KA Neville - Drugs, 2013 - Springer
Over the past 50 years, numerous advances in treatment have produced dramatic increases
in the cure rates of pediatric leukemias. Despite this progress, the majority of children with …
in the cure rates of pediatric leukemias. Despite this progress, the majority of children with …