With the emergence of individualized medicine and the increasing amount and complexity of
available medical data, a growing need exists for the development of clinical decision …

Accurate volumetric assessment in non-small cell lung cancer (NSCLC) is critical for
adequately informing treatments. In this study we assessed the clinical relevance of a …

Purpose In this prospective National Cancer Institute–funded American College of
Radiology Imaging Network/Radiation Therapy Oncology Group cooperative group trial, we …

State-of-the art radiotherapy (RT) techniques have become extremely flexible. As a
consequence, highly conformal target doses in combination with optimal organ-at-risk …

We present a method to implement probabilistic treatment planning of intensity-modulated
radiation therapy using custom software plugins in a commercial treatment planning system …

Background. Maximum, mean and peak SUV of primary tumor at baseline FDG-PET scans,
have often been found predictive for overall survival in non-small cell lung cancer (NSCLC) …

The prognosis of patients with lung cancer has improved over the past years. Patient
selection, optimal sequencing of systemic and local treatments, and better surgical …

Purpose Dynamic contrast-enhanced CT (DCE-CT) quantifies vasculature properties of
tumors, whereas static FDG-PET/CT defines metabolic activity. Both imaging modalities are …

Purpose Four-dimensional positron emission tomography (4D PET) imaging of the thorax
produces sharper images with reduced motion artifacts. Current radiation therapy planning …

Advances in the management of non-small cell lung cancer (NSCLC) over the past 30 years
have led to small increases in 5-year survival rates across Europe, though further …