Isolation of monoclonal antibodies is an important technique for understanding the
specificities and characteristics of antibodies that underlie the humoral immune response to …

Broadly neutralizing antibodies reactive against most and even all variants of the same viral
species have been described for influenza and HIV-1 (ref.). However, whether a neutralizing …

Serum characterization and antibody isolation are transforming our understanding of the
humoral immune response to viral infection. Here, we show that epitope specificities of HIV …

This report describes the design, generation and testing of Ylanthia, a fully synthetic human
Fab antibody library with 1.3 E+ 11 clones. Ylanthia comprises 36 fixed immunoglobulin (Ig) …

Middle East respiratory syndrome coronavirus (MERS-CoV) has recently emerged as a
causative agent of severe respiratory disease in humans. Here, we constructed recombinant …

Today there are many licensed antiviral drugs, but the emergence of drug resistant strains
sometimes invalidates the effects of the current therapies used in the treatment of infectious …

Severe fever with thrombocytopenia syndrome virus (SFTSV), a newly discovered member
of the Bunyaviridae family, is the causative agent of an emerging hemorrhagic fever, SFTS …

Passive immunoprophylaxis or immunotherapy with norovirus-neutralizing monoclonal
antibodies (MAbs) could be a useful treatment for high-risk populations, including infants …

This review highlights the growing importance of protein epitope mimetics in the discovery of
new biologically active molecules and their potential applications in drug and vaccine …

Background Human T cell lymphotropic virus type 1 (HTLV-1) infection can lead to
development of adult T cell leukemia/lymphoma (ATL) or HTLV-1-associated …