• Intensive care unit management of patients with acute traumatic central cord syndrome
(ATCCS), particularly patients with severe neurological deficits, is recommended.• Medical …

Approximately 11 000 people suffer traumatic spinal cord injury (TSCI) in the United States,
each year. TSCI incidences vary from 13.1 to 52.2 per million people and the mortality rates …

Spinal cord injury results in significant mortality and morbidity, lifestyle changes, and difficult
rehabilitation. Treatment of spinal cord injury is challenging because the spinal cord is both …

First introduced into clinical practice in 1969, glibenclamide (US adopted name, glyburide) is
known best for its use in the treatment of diabetes mellitus type 2, where it is used to promote …

In this study we have characterised the locomotor recovery, and temporal profile of cell loss,
in a novel thoracic compression spinal cord injury (SCI) in the mouse. We have also shown …

Approximately one-third of people with a spinal cord injury (SCI) will experience persistent
neuropathic pain following injury. This pain negatively affects quality of life and is difficult to …

Tissues within the central nervous system (CNS) have generally been regarded as
immunologically privileged. However, in recent decades, it has been shown that immune …

Spinal cord trauma causes loss of motor function that is in part due to the ensuing
inflammatory response. Hydrogen sulfide (H2S) is a potent, endogenous anti‐inflammatory …

Study design: Prospective observational study of acute spinal cord-injured (SCI) patients.
Objectives: To determine how effectively mean arterial blood pressure (MAP) and spinal …

Currently, there is no effective strategy for the treatment of spinal cord injury (SCI). A
combination of biomaterials and stem cell therapy seems to be a promising approach to …