Cholangiocarcinomas (CCAs) are hepatobiliary cancers with features of cholangiocyte
differentiation; they can be classified anatomically as intrahepatic CCA (iCCA), perihilar …

Background: Patients suffering from diabetes mellitus (DM) may experience an increased
risk of cancer; however, it is not certain whether this effect is due to diabetes per se …

The associations between diabetes, smoking, obesity, and intrahepatic cholangiocarcinoma
(ICC) risk remain inconclusive. Metformin is purportedly associated with a reduced risk for …

Background To update and compare mortality from primary liver cancer (PLC) and
intrahepatic cholangiocarcinoma (ICC) in Europe in 1990–2010. Materials and methods We …

Background Cholangiocarcinoma, including intra-and extrahepatic cholangiocarcinoma, is a
rare but highly lethal cancer. Despite effort in finding the risk factors of cholangiocarcinoma …

Background Enhancer of zeste homolog 2 (EZH2) is the catalytic subunit of the polycomb
repressive complex 2 (PRC2). When present in PRC2, EZH2 catalyzes trimethylation on …

Purpose To analyse the dynamic enhancing features by real-time contrast-enhanced
ultrasound (CEUS) of intrahepatic peripheral cholangiocarcinoma (ICC) in patients with …

AIM: To assess the association between smoking and alcohol consumption and extrahepatic
cholangiocarcinoma (ECC) through a meta-analysis of clinical observational studies …

Cholangiocarcinoma is the second most common liver cancer in the world. The aetiology of
the disease is diverse incorporating a variety of conditions leading to biliary stasis, biliary …

Liver cirrhosis is a recognized risk factor for intrahepatic cholangiocarcinoma (I‐CC a). Small
I‐CC a nodules might be undiagnosed or misdiagnosed as hepatocellular carcinoma (HCC) …