Sex and gender issues in multiple sclerosis
HF Harbo, R Gold, M Tintoré - Therapeutic advances in …, 2013 - journals.sagepub.com
Multiple sclerosis (MS) is universally found to be more prevalent in women than men. This
has led to extensive studies of differences in the immune system or nervous system between …
has led to extensive studies of differences in the immune system or nervous system between …
Casting light on multiple sclerosis heterogeneity: the role of HLA-DRB1 on spinal cord pathology
GC DeLuca, R Alterman, JL Martin, A Mittal, S Blundell… - Brain, 2013 - academic.oup.com
Clinical heterogeneity in multiple sclerosis is the rule. Evidence suggests that HLA-DRB1*
15 may play a role in clinical outcome. Spinal cord pathology is common and contributes …
15 may play a role in clinical outcome. Spinal cord pathology is common and contributes …
Association of HLA-DRB1* 1501 tagging rs3135388 gene polymorphism with multiple sclerosis
Y Benešová, A Vašků, P Štourač, M Hladíková… - Journal of …, 2013 - Elsevier
We investigated the HLA-DRB1* 1501 tagging rs3135388 gene polymorphism and its
association with multiple sclerosis (MS) susceptibility, disability and gender differences. The …
association with multiple sclerosis (MS) susceptibility, disability and gender differences. The …
Prevalence of cerebrospinal fluid oligoclonal IgG bands in Greek patients with clinically isolated syndrome and multiple sclerosis
E Andreadou, S Chatzipanagiotou… - Clinical neurology and …, 2013 - Elsevier
Lower prevalence of cerebrospinal fluid oligoclonal IgG bands (IgG-OCBs) has been
reported in multiple sclerosis (MS) patients from Southern Europe compared to other …
reported in multiple sclerosis (MS) patients from Southern Europe compared to other …
Multiple sclerosis susceptibility loci do not alter clinical and MRI outcomes in clinically isolated syndrome
T Kalincik, CRG Guttmann, J Krasensky… - Genes & …, 2013 - nature.com
It has not yet been established whether genetic predictors of multiple sclerosis (MS)
susceptibility also influence disease severity and accumulation of disability. Our aim was to …
susceptibility also influence disease severity and accumulation of disability. Our aim was to …
Genetic factors and multiple sclerosis in the Moroccan population: A role for HLA class II
S Ouadghiri, KEA Toussi, C Brick, EHA Benhaddou… - Pathologie …, 2013 - Elsevier
Background and objective Multiple sclerosis (MS) is an autoimmune inflammatory
demyelinating disease of the central nervous system that mainly affects young adults. The …
demyelinating disease of the central nervous system that mainly affects young adults. The …
A NOTCH4 missense mutation confers resistance to multiple sclerosis in Japanese
J Huang, S Yoshimura, N Isobe… - Multiple Sclerosis …, 2013 - journals.sagepub.com
Background: The G allele of NOTCH4 rs422951 is protective against demyelinating disease
in Japanese. Objectives: The purpose of this study was to assess the relation of the G allele …
in Japanese. Objectives: The purpose of this study was to assess the relation of the G allele …
Polyreactive monoclonal autoantibodies in multiple sclerosis: functional selection from phage display library and characterization by deep sequencing analysis
YA Lomakin, MY Zakharova, AA Belogurov… - Acta Naturae …, 2013 - cyberleninka.ru
Multiple Sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system that primarily affects young and middle-aged people. It is widely accepted …
nervous system that primarily affects young and middle-aged people. It is widely accepted …
Considerations for subgroups and phenocopies in complex disease genetics
R Ramanujam, S Ramanujam, J Hillert - Plos one, 2013 - journals.plos.org
The number of identified genetic variants associated to complex disease cannot fully explain
heritability. This may be partially due to more complicated patterns of predisposition than …
heritability. This may be partially due to more complicated patterns of predisposition than …
Design and Implementation of a Computational Platform and a Parallelized Interaction Analysis for Large Scale Genomics Data in Multiple Sclerosis
D Uvehag - 2013 - diva-portal.org
The multiple sclerosis (MS) genetics research group led by professor Jan Hillert at
Karolinska Institutet, focuses on investigating the aetiology of the disease. Samples have …
Karolinska Institutet, focuses on investigating the aetiology of the disease. Samples have …