The generation, detection, and effects of reactive drug metabolites

AV Stachulski, TA Baillie, B Kevin Park… - Medicinal research …, 2013 - Wiley Online Library
The decline in approval of new drugs during the past decade has led to a close analysis of
the drug discovery process. One of the main reasons for attrition is preclinical toxicity …

Penetration and haptenation of p‐phenylenediamine

LM Pot, SM Scheitza, PJ Coenraads… - Contact …, 2013 - Wiley Online Library
Although p‐phenylenediamine (PPD) has been recognized as an extreme sensitizer for
many years, the exact mechanism of sensitization has not been elucidated yet. Penetration …

[PDF][PDF] Étude électrochimique de l'oxydation de la ParaPhénylèneDiamine (PPD) sur platine dans H2SO4 (0, 5M)

R Srhayri, N Habti, D Takky, S Motaouakkil… - Journal of Materials …, 2013 - asjp.cerist.dz
La p-phénylènediamine (PPD) est une amine aromatique d'origine minérale dérivée de
l'aniline, couramment utilisée dans l'industrie [1-2-3]. L'objectif de ce travail est d'étudier …