Free radicals are chemical particles containing one or more unpaired electrons, which may
be part of the molecule. They cause the molecule to become highly reactive. The free …

Autophagy and senescence share a number of characteristics, which suggests that both
responses could serve to collaterally protect the cell from the toxicity of external stress such …

Abstract Compound K (20-O-(β-D-glucopyranosyl)-20 (S)-protopanaxadiol) is an active
metabolite of ginsenosides and induces apoptosis in various types of cancer cells. This …

Curcumin was determined to have anticancer potency on several kinds of carcinoma.
However, its medical application was limited because of its poor bioavailability, unsatisfying …

Much evidence indicates that various naturally occurring compounds have an anti-cancer
effect, but the detailed mechanisms are not well understood. In this study, we selected anti …

Autophagy (macroautophagy) is an evolutionarily conserved lysosomal degradation
process, in which a cell degrades long-lived proteins and damaged organelles. Recently …

Hepatocellular carcinoma (HCC) is the most prevalent type of liver cancer globally and
ranks first among the cancer-related mortalities in Taiwan. This study aims to understand the …

In Cuba the endemic species of scorpion Rhopalurus junceus has been used in traditional
medicine for cancer treatment. However, there is little scientific evidence about its potential …

Since centuries, natural compounds from plants, animals and microorganisms were used in
medicinal traditions to treat various diseases without a solid scientific basis. Recent studies …

The deregulation of oncogenic signaling pathways which provide survival advantages to
tumor cells is mediated by multiple cellular networks. Among them, the PI3K-Akt-mTOR axis …