Oncogenes induce the cancer-associated fibroblast phenotype: metabolic symbiosis and “fibroblast addiction” are new therapeutic targets for drug discovery
MP Lisanti, UE Martinez-Outschoorn, F Sotgia - Cell cycle, 2013 - Taylor & Francis
Metabolic coupling, between mitochondria in cancer cells and catabolism in stromal
fibroblasts, promotes tumor growth, recurrence, metastasis, and predicts anticancer drug …
fibroblasts, promotes tumor growth, recurrence, metastasis, and predicts anticancer drug …
[HTML][HTML] Cancer metabolism: new validated targets for drug discovery
F Sotgia, UE Martinez-Outschoorn, MP Lisanti - Oncotarget, 2013 - ncbi.nlm.nih.gov
Recent studies in cancer metabolism directly implicate catabolic fibroblasts as a new rich
source of i) energy and ii) biomass, for the growth and survival of anabolic cancer cells …
source of i) energy and ii) biomass, for the growth and survival of anabolic cancer cells …