CD133 as a biomarker for putative cancer stem cells in solid tumours: limitations, problems and challenges

P Grosse‐Gehling, CA Fargeas, C Dittfeld… - The Journal of …, 2013 - Wiley Online Library
The cancer stem cell (CSC) hypothesis, despite the limitations of the currently available
models and assays, has ushered in a new era of excitement in cancer research. The …

Glioma and glioblastoma‑how much do we (not) know?

I Jovčevska, N Kočevar… - … and clinical oncology, 2013 - spandidos-publications.com
Cancer is a heterogeneous disease, which provides a broad field for investigation, while
simultaneously reducing the chances for a universal treatment. Malignant gliomas are the …

CD133+ cells with cancer stem cell characteristics associates with vasculogenic mimicry in triple-negative breast cancer

TJ Liu, BC Sun, XL Zhao, XM Zhao, T Sun, Q Gu, Z Yao… - Oncogene, 2013 - nature.com
Vasculogenic mimicry (VM) refers to the unique capability of aggressive tumor cells to mimic
the pattern of embryonic vasculogenic networks. In the study we demonstrated that CD133 …

Proximal tubular cells contain a phenotypically distinct, scattered cell population involved in tubular regeneration

B Smeets, P Boor, H Dijkman, SV Sharma… - The Journal of …, 2013 - Wiley Online Library
Regeneration of injured tubular cells occurs after acute tubular necrosis primarily from
intrinsic renal cells. This may occur from a pre‐existing intratubular stem/progenitor cell …

CD133-targeted paclitaxel delivery inhibits local tumor recurrence in a mouse model of breast cancer

SK Swaminathan, E Roger, U Toti, L Niu… - Journal of Controlled …, 2013 - Elsevier
Expression of the membrane protein CD133 marks a subset of cancer cells with drug
resistant phenotype and enhanced tumor initiating ability in xenotransplantation assays …

Oocyte developmental failure in response to elevated nonesterified fatty acid concentrations: mechanistic insights

V Van Hoeck, J Leroy, MA Alvarez, D Rizos… - …, 2013 - rep.bioscientifica.com
The aim of this study was to evaluate the distribution of inhibin/activin alpha, beta (A) and
beta (B) subunits and follistatin in immature oocytes and in matured oocytes before and after …

[HTML][HTML] CD133: to be or not to be, is this the real question?

E Irollo, G Pirozzi - American journal of translational research, 2013 - ncbi.nlm.nih.gov
Abstract CD133 (prominin-1) is a member of the transmembrane glycoprotein family and
was initially described as a specific marker to select human hematopoietic progenitor cells …

Cytokine-induced killer (CIK) cells bound with anti-CD3/anti-CD133 bispecific antibodies target CD133high cancer stem cells in vitro and in vivo

J Huang, C Li, Y Wang, H Lv, Y Guo, H Dai… - Clinical …, 2013 - Elsevier
CD133 is a common marker of cancer stem cells (CSCs). We generated an anti-CD3/anti-
CD133 bispecific antibody (BsAb) and bound it to the cytokine-induced killer (CIK) cells as …

Clinical significances and prognostic value of cancer stem‐like cells markers and vasculogenic mimicry in renal cell carcinoma

Y Zhang, B Sun, X Zhao, Z Liu, X Wang… - Journal of surgical …, 2013 - Wiley Online Library
Background The aim of this study was to investigate the clinical significances and prognostic
value of CD133 and CD44 (markers of cancer stem‐like cells, CSCs), and vasculogenic …

The stem cell marker prominin-1/CD133 interacts with vascular endothelial growth factor and potentiates its action

A Adini, I Adini, K Ghosh, O Benny, E Pravda, R Hu… - Angiogenesis, 2013 - Springer
Prominin-1, a pentaspan transmembrane protein, is a unique cell surface marker commonly
used to identify stem cells, including endothelial progenitor cells and cancer stem cells …