Nonsense-mediated mRNA decay (NMD) is a eukaryotic post-transcriptional gene
regulation mechanism that eliminates mRNAs with the termination codon (TC) located in an …

The multiprotein exon junction complex (EJC), deposited by the splicing machinery, is an
important constituent of messenger ribonucleoprotein particles because it participates to …

The mechanisms that underlie the ability of some introns to increase gene expression, a
phenomenon called intron-mediated enhancement (IME), are not fully understood. It is also …

DEAD-box proteins are involved in all aspects of RNA processing. They bind RNA in an ATP-
dependent manner and couple ATP hydrolysis to structural and compositional …

RBM8A (Y14) contains an RNA-binding motif and forms a tight heterodimer with Magoh. The
heterodimer is known to be a member of the exon junction complex that forms on mRNA …

The exon junction complex (EJC) participates in the regulation of many post-transcriptional
steps of gene expression. EJCs are deposited on messenger RNAs (mRNAs) during …

The ability to distinguish self from non-self nucleic acids enables eukaryotes to suppress
mobile elements and maintain genome integrity. In organisms from protist to human, this …

The exon junction complex (EJC) is highly conserved in many organisms and is involved in
various steps of mRNA metabolism. During the course of investigating the role of EJC in the …

Well known for its potential for industrial applications detailed in other chapters of this book,
Yarrowia lipolytica occupies an interesting position among hemiascomycetous yeasts due to …

Nonsense-mediated mRNA decay (NMD) is a pathway that detects and degrades mRNAs
containing premature translation termination codons (PTCs). In humans, recognition of these …