Brain regulation of energy balance and body weight

L Rui - Reviews in Endocrine and Metabolic Disorders, 2013 - Springer
Body weight is determined by a balance between food intake and energy expenditure.
Multiple neural circuits in the brain have evolved to process information about food, food …

Selective leptin resistance revisited

AL Mark - … Journal of Physiology-Regulatory, Integrative and …, 2013 - journals.physiology.org
In addition to effects on appetite and metabolism, leptin influences many neuroendocrine
and physiological systems, including the sympathetic nervous system. Building on my Carl …

Leptin activates oxytocin neurons of the hypothalamic paraventricular nucleus in both control and diet-induced obese rodents

M Perello, J Raingo - PloS one, 2013 - journals.plos.org
The adipocyte-derived hormone leptin acts in the brain to reduce body weight and fat mass.
Recent studies suggest that parvocellular oxytocin (OXT) neurons of the hypothalamic …

Neonatal leptin exposure specifies innervation of presympathetic hypothalamic neurons and improves the metabolic status of leptin-deficient mice

K Bouyer, RB Simerly - Journal of Neuroscience, 2013 - Soc Neuroscience
The paraventricular nucleus of the hypothalamus (PVH) consists of distinct functional
compartments regulating neuroendocrine, behavioral, and autonomic activities that are …

Obesity, adipokines and metabolic syndrome in polycystic ovary syndrome

E Carmina - Polycystic Ovary Syndrome, 2013 - karger.com
The complex mechanisms linking fat excess to metabolic syndrome are not well understood,
but several experimental studies have shown that altered production of adipokines plays a …

Leptin stimulates neuropeptide Y and cocaine amphetamine-regulated transcript coexpressing neuronal activity in the dorsomedial hypothalamus in diet-induced …

SJ Lee, S Verma, SE Simonds, MA Kirigiti… - Journal of …, 2013 - Soc Neuroscience
Neuropeptide Y (NPY) neurons in both the arcuate nucleus of the hypothalamus (ARH) and
the dorsomedial hypothalamus (DMH) have been implicated in food intake and obesity …

Overview of the physiology and pathophysiology of leptin with special emphasis on its role in the kidney

MP Nasrallah, FN Ziyadeh - Seminars in nephrology, 2013 - Elsevier
The adipocyte product leptin is a pleiotropic adipokine and hormone, with a role extending
beyond appetite suppression and increased energy expenditure. This review summarizes …

Hypertension in obesity: is leptin the culprit?

SE Simonds, MA Cowley - Trends in neurosciences, 2013 - cell.com
The number of obese or overweight humans continues to increase worldwide. Hypertension
is a serious disease that often develops in obesity, but it is not clear how obesity increases …

Integration of sensory information via central thermoregulatory leptin targets

K Rezai-Zadeh, H Münzberg - Physiology & behavior, 2013 - Elsevier
The adipocyte derived hormone leptin acts in the brain to regulate body weight, food intake
and energy expenditure. Even though it is well accepted that leptin regulates energy …

Chemoreceptors, baroreceptors, and autonomic deregulation in children with obstructive sleep apnea

D Gozal, F Hakim, L Kheirandish-Gozal - Respiratory physiology & …, 2013 - Elsevier
Obstructive sleep apnea (OSA) is highly prevalent sleep disorder of breathing in both adults
and children that is fraught with substantial cardiovascular morbidities, the latter being …