Diagnosis of Clostridium difficile infection: an ongoing conundrum for clinicians and for clinical laboratories
BD Carey-Ann, KC Carroll - Clinical microbiology reviews, 2013 - Am Soc Microbiol
Clostridium difficile is a formidable nosocomial and community-acquired pathogen, causing
clinical presentations ranging from asymptomatic colonization to self-limiting diarrhea to …
clinical presentations ranging from asymptomatic colonization to self-limiting diarrhea to …
Modern clinical microbiology: new challenges and solutions
PE Fournier, M Drancourt, P Colson… - Nature Reviews …, 2013 - nature.com
In the twenty-first century, the clinical microbiology laboratory plays a central part in
optimizing the management of infectious diseases and surveying local and global …
optimizing the management of infectious diseases and surveying local and global …
Diverse Sources of C. difficile Infection Identified on Whole-Genome Sequencing
Background It has been thought that Clostridium difficile infection is transmitted
predominantly within health care settings. However, endemic spread has hampered …
predominantly within health care settings. However, endemic spread has hampered …
Automated analysis of phylogenetic clusters
Background As sequence data sets used for the investigation of pathogen transmission
patterns increase in size, automated tools and standardized methods for cluster analysis …
patterns increase in size, automated tools and standardized methods for cluster analysis …
Current application and future perspectives of molecular typing methods to study Clostridium difficile infections
CW Knetsch, TD Lawley, MP Hensgens… - …, 2013 - eurosurveillance.org
Molecular typing is an essential tool to monitor Clostridium difficile infections and outbreaks
within healthcare facilities. Molecular typing also plays a key role in defining the regional …
within healthcare facilities. Molecular typing also plays a key role in defining the regional …
The globalization of healthcare: implications of medical tourism for the infectious disease clinician
LH Chen, ME Wilson - Clinical infectious diseases, 2013 - academic.oup.com
Travel abroad for healthcare has increased rapidly; interventions include organ transplant;
cardiac surgery; reproductive care; and joint, cosmetic, and dental procedures. Individuals …
cardiac surgery; reproductive care; and joint, cosmetic, and dental procedures. Individuals …
Clostridium difficile infection in the twenty-first century
C Ghose - Emerging microbes & infections, 2013 - Taylor & Francis
Clostridium difficile is a spore-forming gram-positive bacillus, and the leading cause of
antibiotic-associated nosocomial diarrhea and colitis in the industrialized world. With the …
antibiotic-associated nosocomial diarrhea and colitis in the industrialized world. With the …
The agr Locus Regulates Virulence and Colonization Genes in Clostridium difficile 027
MJ Martin, S Clare, D Goulding… - Journal of …, 2013 - Am Soc Microbiol
The transcriptional regulator AgrA, a member of the LytTR family of proteins, plays a key role
in controlling gene expression in some Gram-positive pathogens, including Staphylococcus …
in controlling gene expression in some Gram-positive pathogens, including Staphylococcus …
Clostridium difficile in foods and animals: history and measures to reduce exposure
A Rodriguez-Palacios, S Borgmann… - Animal health …, 2013 - cambridge.org
Many articles have summarized the changing epidemiology of Clostridium difficile infections
(CDI) in humans, but the emerging presence of C. difficile in foods and animals and possible …
(CDI) in humans, but the emerging presence of C. difficile in foods and animals and possible …
Neutral Genomic Microevolution of a Recently Emerged Pathogen, Salmonella enterica Serovar Agona
Salmonella enterica serovar Agona has caused multiple food-borne outbreaks of
gastroenteritis since it was first isolated in 1952. We analyzed the genomes of 73 isolates …
gastroenteritis since it was first isolated in 1952. We analyzed the genomes of 73 isolates …