Mucinous differentiation is associated with both CpG island methylator phenotype and
microsatellite instability in colorectal cancer. The mucinous phenotype derives from …

Background Despite regular surveillance colonoscopy, the metachronous colorectal cancer
risk for mismatch repair (MMR) gene mutation carriers after segmental resection for colon …

Methods A group of 33 patients with colorectal cancer was randomly selected from the
department of surgery bio-bank to determine the expression of MMR proteins in their FFPE …

The serrated neoplastic pathway accounts for approximately 30% of colorectal cancers.
Characterized by mutations in the oncogene BRAF, DNA promoter hypermethylation, and …

We aimed to determine semiquantitative evaluation criteria for Crohn-like lymphoid reaction
(CLR). We reviewed 1,032 patients with colorectal cancer and evaluated CLR by counting …

Abstract Analysis of synchronous colorectal carcinomas can provide a unique model to
examine the underlying molecular alterations in colorectal carcinoma, as synchronous …

Background & Aims Colorectal tumors have a large degree of molecular heterogeneity.
Three integrated pathways of carcinogenesis (ie, traditional, alternate, and serrated) have …

We evaluated a consecutive series of signet ring cell colorectal carcinomas in an attempt to
correlate the histopathologic pattern of infiltration with molecular alterations and prognosis …

Colorectal cancer is an invasive neoplasm of the glandular epithelium of the colon and
rectum that begins in a precursor lesion and expands to replace its lesion of origin. The …

The optimal strategy for screening patients with colorectal carcinoma for Lynch syndrome
(LS) is a subject of continued debate in the literature with some advocating universal …