Targeting erythropoietin for chronic neurodegenerative diseases

ZZ Chong, YC Shang, Y Mu, S Cui, Q Yao… - Expert opinion on …, 2013 - Taylor & Francis
Introduction: Since erythropoietin (EPO) and EPO receptor (EPOR) are expressed in the
central nervous system (CNS) beyond hematopoietic system, EPO illustrates a robust …

The glycogen synthase kinase-3β/nuclear factor-kappa B pathway is involved in cinobufagin-induced apoptosis in cultured osteosarcoma cells

J Yin, L Wen, L Wu, Z Gao, G Huang, J Wang, C Zou… - Toxicology Letters, 2013 - Elsevier
Cinobufagin, a major component of cinobufacini (huachansu), is an important cardenolidal
steroid. Several studies have suggested that cinobufagin has potent anti-cancer effects. The …

[HTML][HTML] Increase in retinal ganglion cells' susceptibility to elevated intraocular pressure and impairment of their endogenous neuroprotective mechanism by age

H Levkovitch-Verbin, S Vander, D Makarovsky… - Molecular …, 2013 - ncbi.nlm.nih.gov
Purpose To investigate age-associated changes in retinal ganglion cell (RGC) response to
elevated intraocular pressure (IOP), and to explore the mechanism underlying these …

Overexpression of p65 attenuates celecoxib-induced cell death in MDA-MB-231 human breast cancer cell line

L Wang, F Kang, J Li, J Zhang, B Shan - Cancer Cell International, 2013 - Springer
Background Celecoxib is a selective cyclooxygenase (COX)-2 inhibitor that has been
reported to reduce the risk of breast cancer. In our previous study, celecoxib induced …