Abstract Background The Amoebozoa constitute one of the primary divisions of eukaryotes,
encompassing taxa of both biomedical and evolutionary importance, yet its genomic …

DIVERGE is a software system for phylogeny-based analyses of protein family evolution and
functional divergence. It provides a suite of statistical tools for selection and prioritization of …

Genome sequencing of arguably the simplest known animal, Trichoplax adhaerens,
uncovered a rich array of transcription factor and signalling pathway genes. Although the …

Tyrosine depletion in metazoan proteins was recently explained to be due to the
appearance of tyrosine kinases in Metazoa. Here, we present a complementary explanation …

The proportion of guanine (G) or cytosine (C) nucleotide bases in the human genome is
approximately 40%. Fluctuating relatively to this averaged G+ C content, there are large …

Amino acids are the building blocks of proteins, and the composition of those proteins plays
a major role in cell signaling. Recently, Tan et al. showed that the overall frequency of the …