BACKGROUND: Increasing population-based studies have suggested a relationship
between psoriasis and metabolic syndrome. OBJECTIVE: The objective of this study was to …

Pre-B cell colony enhancing factor (PBEF) is regarded as a proinflammatory cytokine.
Named for its first discovered function as a pre-B cell colony enhancing factor, it has since …

Background Chronic plaque psoriasis is associated with obesity, which is a metabolic and
inflammatory disorder. Adipokines are involved in the pathogenesis of psoriasis and they …

The pathogenetic mechanisms responsible for the induction of immune‐mediated disorders,
such as psoriasis, remain not well characterized. Molecular signaling pathways are not well …

The “cholinergic anti-inflammatory pathway” provides neurological modulation of cytokine
synthesis to limit the magnitude of the immune response. This study aimed to evaluate the …

Cellular quiescence is a reversible cell cycle arrest that is poised to re-enter the cell cycle in
response to a combination of cell-intrinsic factors and environmental cues. In hematopoietic …

Background Psoriasis is a chronic autoimmune disease in which T cells have a predominant
role in initiating and perpetuating the chronic inflammation in skin. However, the …

Crohn's disease (CD) and ulcerative colitis (UC) are the two common forms of idiopathic
inflammatory bowel disease (IBD). The aetiology and pathogenesis of IBD are not yet …

Psoriasis has been lately seen as a potential systemic inflammatory disease associated with
a range of comorbidities exhibiting an overlapping pathology and presenting a great social …

烟酰胺磷酸核糖转移酶(nicotinamide phosphoribosyl transferase, NAMPT)
是烟酰胺腺瞟呤二核苷酸(nicotinamide adenine dinucleotide, NAD+) 补救合成途径的限速酶 …