Cathepsin B as a cancer target

CS Gondi, JS Rao - Expert opinion on therapeutic targets, 2013 - Taylor & Francis
Introduction: Cathepsin B is of significant importance to cancer therapy as it is involved in
various pathologies and oncogenic processes in humans. Numerous studies have shown …

[HTML][HTML] Aberrant promoter CpG methylation and its translational applications in breast cancer

TX Xiang, Y Yuan, LL Li, ZH Wang, LY Dan… - Chinese journal of …, 2013 - ncbi.nlm.nih.gov
Breast cancer is a complex disease driven by multiple factors including both genetic and
epigenetic alterations. Recent studies revealed that abnormal gene expression induced by …

[HTML][HTML] Recent progress in the study of methylated tumor suppressor genes in gastric cancer

XT Hu, C He - Chinese Journal of Cancer, 2013 - ncbi.nlm.nih.gov
Gastric cancer is one of the most common malignancies and a leading cause of cancer
mortality worldwide. The pathogenesis mechanisms of gastric cancer are still not fully clear …

[HTML][HTML] Caveolin-1 Protects B6129 Mice against Helicobacter pylori Gastritis

I Hitkova, G Yuan, F Anderl, M Gerhard… - PLoS …, 2013 - journals.plos.org
Caveolin-1 (Cav1) is a scaffold protein and pathogen receptor in the mucosa of the
gastrointestinal tract. Chronic infection of gastric epithelial cells by Helicobacter pylori (H …

[HTML][HTML] Promoter methylation of the DLC‑1 gene and its inhibitory effect on human colon cancer

Z Dai, Y Jin - Oncology Reports, 2013 - spandidos-publications.com
Deleted in liver cancer‑1 (DLC‑1), a candidate tumor suppressor gene which is inactive in
liver carcinogenesis, is located at 8p21. 3, where deletions are frequently found in several …

START-GAP/DLC Family Proteins: Molecular Mechanisms for Anti-Tumor Activities

H Yagisawa - Future aspects of tumor suppressor gene, 2013 - books.google.com
The Rho family of GTPases belongs to the superfamily named “Ras-like” proteins, which
consists of over 150 varieties in mammals [1]. Significant progress has recently been made …

[引用][C] miR-19a 在结肠癌中高表达以及通过靶定DLC1 促进结肠癌细胞增殖

郭运生, 戚峰, 刘彤, 王益民, 周文阔 - 天津医科大学学报, 2013

[引用][C] 肝癌缺失基因1 与原发性肝癌的研究进展

彭鹏, 胡泽民 - 中华普通外科学文献: 电子版, 2013