Highlights•Modern neurotrophin delivery systems should be able to cure neuronal
loss.•Gene carriers deliver stable neurotrophic proteins to specific brain regions.•Delivery …

With their high‐surface‐to‐volume ratio, nanofibers have been postulated to increase
interactions between nanofibrous materials and targeted substrates, which are helpful to …

The foreign body reaction often interferes with the long-term functionality and performance of
implanted biomedical devices through fibrous capsule formation. While many implant …

Highlights•Commercial nerve guidance conduits are insufficient to promote enhanced
regeneration.•Multifaceted approaches are needed to mimic native nerve architecture and …

Polycaprolactone (PCL)/Pluronic F127 nerve guide conduits (NGCs) with different surface
pore structures (nano-porous inner surface vs. micro-porous inner surface) but similar …

Repair of peripheral nerve defects with current synthetic, tubular nerve conduits generally
shows inferior recovery when compared with using nerve autografts, the current gold …

Three dimensional (3D) conduits facilitate nerve regeneration. Parallel microfibers have
been shown to guide axon extension and Schwann cell migration on flat sheets via …

Controlling the structure and organization of electrospun fibers is desirable for fabricating
scaffolds and materials with defined microstructures. However, the effects of …

Novel peripheral nerve conduits containing the negatively charged Tremella fuciformis
polysaccharide (TF) were prepared, and their efficacy in bridging a critical nerve gap was …

Since its inception, the field of tissue engineering has sought to rebuild the complexity of
normal tissues by seeding cells onto scaffolds to support the formation of new tissue …