Toll-like receptors (TLRs) are type I transmembrane proteins that are key regulators of both
innate and adaptive immune responses. To protect the host from viral and bacterial threats …

Ortho-lithiated styrenes or ortho-lithiated benzaldehyde dimethyl acetals were added to 2, 2-
dimethoxypent-4-enals 7. The resulting alcohols were carried on to the aromatic dienones …

Abstract The National Cancer Institute Diversity Set II (1356 compounds) and Diversity Set III
(1597 compounds) were screened via in silico methods as potential inhibitors of low …

Toll-like receptors (TLRs) play a pivotal role in the onset of innate immunity against invading
microbial. Recently, they have been identified as potential drug-targets due to their role in …

Chloroperoxidase (CPO) from Caldariomyces fumago is a very versatile heme enzyme that
catalyzes different reaction types, including peroxidation reactions of various substrates …

The field of immunology has become increasingly lucid at the level of atoms and molecules.
Owing also to advances in synthetic chemistry, the rational design and construction of …

Antibodies are a central component of the adaptive immune system, which has evolved to
be able to produce antibodies with high specificity and affinity to a multitude of target …