The sensory neurons of touch
VE Abraira, DD Ginty - neuron, 2013 - cell.com
The somatosensory system decodes a wide range of tactile stimuli and thus endows us with
a remarkable capacity for object recognition, texture discrimination, sensory-motor feedback …
a remarkable capacity for object recognition, texture discrimination, sensory-motor feedback …
Neural processing of itch
T Akiyama, E Carstens - Neuroscience, 2013 - Elsevier
While considerable effort has been made to investigate the neural mechanisms of pain,
much less effort has been devoted to itch, at least until recently. However, itch is now gaining …
much less effort has been devoted to itch, at least until recently. However, itch is now gaining …
Drosophila NOMPC is a mechanotransduction channel subunit for gentle-touch sensation
Touch sensation is essential for behaviours ranging from environmental exploration to social
interaction; however, the underlying mechanisms are largely unknown. In Drosophila larvae …
interaction; however, the underlying mechanisms are largely unknown. In Drosophila larvae …
A feed-forward spinal cord glycinergic neural circuit gates mechanical allodynia
Y Lu, H Dong, Y Gao, Y Gong, Y Ren… - The Journal of …, 2013 - Am Soc Clin Investig
Neuropathic pain is characterized by mechanical allodynia induced by low-threshold
myelinated Aβ-fiber activation. The original gate theory of pain proposes that inhibitory …
myelinated Aβ-fiber activation. The original gate theory of pain proposes that inhibitory …
Genetic identification of C fibres that detect massage-like stroking of hairy skin in vivo
S Vrontou, AM Wong, KK Rau, HR Koerber… - Nature, 2013 - nature.com
Stroking of the skin produces pleasant sensations that can occur during social interactions
with conspecifics, such as grooming. Despite numerous physiological studies (reviewed in …
with conspecifics, such as grooming. Despite numerous physiological studies (reviewed in …
An extracellular adhesion molecule complex patterns dendritic branching and morphogenesis
Robust dendrite morphogenesis is a critical step in the development of reproducible neural
circuits. However, little is known about the extracellular cues that pattern complex dendrite …
circuits. However, little is known about the extracellular cues that pattern complex dendrite …
[HTML][HTML] Skin-derived cues control arborization of sensory dendrites in Caenorhabditis elegans
Y Salzberg, CA Díaz-Balzac, NJ Ramirez-Suarez… - Cell, 2013 - cell.com
Sensory dendrites depend on cues from their environment to pattern their growth and direct
them toward their correct target tissues. Yet, little is known about dendrite-substrate …
them toward their correct target tissues. Yet, little is known about dendrite-substrate …
[HTML][HTML] TAFA4, a chemokine-like protein, modulates injury-induced mechanical and chemical pain hypersensitivity in mice
MC Delfini, A Mantilleri, S Gaillard, J Hao, A Reynders… - Cell reports, 2013 - cell.com
C-low-threshold mechanoreceptors (C-LTMRs) are unique among C-unmyelinated primary
sensory neurons. These neurons convey two opposite aspects of touch sensation: a …
sensory neurons. These neurons convey two opposite aspects of touch sensation: a …
Runx1 controls terminal morphology and mechanosensitivity of VGLUT3-expressing C-mechanoreceptors
VGLUT3-expressing unmyelinated low-threshold mechanoreceptors (C-LTMRs) are
proposed to mediate pleasant touch and/or pain, but the molecular programs controlling C …
proposed to mediate pleasant touch and/or pain, but the molecular programs controlling C …
Kv1. 1 channels act as mechanical brake in the senses of touch and pain
J Hao, F Padilla, M Dandonneau, C Lavebratt… - Neuron, 2013 - cell.com
Molecular determinants of threshold sensitivity of mammalian mechanoreceptors are
unknown. Here, we identify a mechanosensitive (MS) K+ current (I Kmech) that governs …
unknown. Here, we identify a mechanosensitive (MS) K+ current (I Kmech) that governs …