Background The relevance of mitochondrial dysfunction as to pathogenesis of multiple
organ dysfunction and failure in sepsis is controversial. This focused review evaluates the …

The intense systemic inflammatory response characterizing septic shock is associated with
an increased generation of free radicals by multiple cell types in cardiovascular and non …

Peroxynitrite (ONOO−) formation in mitochondria may be favored due to the constant supply
of superoxide radical (O2-) by the electron transport chain plus the facile diffusion of nitric …

ICU acquired neuromyopathy (IANM) is the most frequent neurological pathology observed
in ICU. Nerve and muscle defects are merged with neuromuscular junction abnormalities. Its …

Background: Vascular hyporeactivity and hyperpolarization are important causes of
circulatory failure in septic shock. However, there is no data on the differences in vascular …