The optical neural recording techniques are promising tools in recent years. Compared to
the traditional electrophysiological recording, the optical means offer several advantages …

Normal mitochondrial function in the process of metabolic energy production is a key factor
in maintaining cellular activities. Many pathological conditions in animals, as well as in …

Because of their favorable action profiles in humans, both memantine and melatonin are
particularly interesting candidates as neuroprotectants in acute ischemic stroke. Until now …

This paper describes a novel optical method for label-free quantitative imaging of cerebral
blood flow (CBF) and intracellular motility (IM) in the rodent cerebral cortex. This method is …

Stroke is a worldwide medical emergency and an important issue in stroke research is
looking for the early pathophysiological markers which can predict the severity of brain …

Stroke is the fourth leading cause of death in the United States and the leading cause of
long-term disability. Ischemic stroke, due to an interruption in blood supply, is particularly …

Background Anesthetic agents alter microcirculation, influencing tissue oxygenation and
delivery of vital substrates. Laser Doppler perfusion imaging is a widespread technique in …

Stroke is a leading cause of death, disability, and socioeconomic loss worldwide. The
majority of all strokes result from an interruption in blood flow (ischemia) 1. Middle cerebral …

Functional imaging of intrinsic signals allows minimally invasive spatiotemporal mapping of
stimulus representations in the cortex, but representations are often corrupted by stimulus …

Normal brain activity is an integration of many biochemical and physiological processes
including hemodynamic, metabolic, ionic homeostasis and electrical activities. In order to …