The in vivo biofilm
T Bjarnsholt, M Alhede, M Alhede… - Trends in …, 2013 - cell.com
Bacteria can grow and proliferate either as single, independent cells or organized in
aggregates commonly referred to as biofilms. When bacteria succeed in forming a biofilm …
aggregates commonly referred to as biofilms. When bacteria succeed in forming a biofilm …
Applying insights from biofilm biology to drug development—can a new approach be developed?
Most of the research on bacterial pathogenesis has focused on acute infections, but much
less is known about the pathogenesis of infections caused by bacteria that grow as …
less is known about the pathogenesis of infections caused by bacteria that grow as …
The role of bacterial biofilms in chronic infections
T Bjarnsholt - Apmis, 2013 - Wiley Online Library
Acute infections caused by pathogenic bacteria have been studied extensively for well over
100 years. These infections killed millions of people in previous centuries, but they have …
100 years. These infections killed millions of people in previous centuries, but they have …
Host responses in tissue repair and fibrosis
JS Duffield, M Lupher, VJ Thannickal… - Annual Review of …, 2013 - annualreviews.org
Myofibroblasts accumulate in the spaces between organ structures and produce
extracellular matrix (ECM) proteins, including collagen I. They are the primary “effector” cells …
extracellular matrix (ECM) proteins, including collagen I. They are the primary “effector” cells …
Microanatomy at cellular resolution and spatial order of physiological differentiation in a bacterial biofilm
Bacterial biofilms are highly structured multicellular communities whose formation involves
flagella and an extracellular matrix of adhesins, amyloid fibers, and exopolysaccharides …
flagella and an extracellular matrix of adhesins, amyloid fibers, and exopolysaccharides …
Biofilm-associated infections: antibiotic resistance and novel therapeutic strategies
F Sun, F Qu, Y Ling, P Mao, P Xia, H Chen… - Future …, 2013 - Taylor & Francis
Infections with bacterial or fungal biofilms have emerged as a major public heath concern
because biofilm-growing cells are highly resistant to both antibiotics and host immune …
because biofilm-growing cells are highly resistant to both antibiotics and host immune …
EWMA document: antimicrobials and non-healing wounds: evidence, controversies and suggestions
F Gottrup, J Apelqvist, T Bjarnsholt… - Journal of wound …, 2013 - magonlinelibrary.com
JOURNAL OF WOUND CARE VOL 22. NO 5. EWMA DOCUMENT 2013 S5 year, 11 of
which more than half are drug-resistant. 12 Infections based on resistant bacteria are …
which more than half are drug-resistant. 12 Infections based on resistant bacteria are …
[HTML][HTML] Complete Genome Sequence of the Cystic Fibrosis Pathogen Achromobacter xylosoxidans NH44784-1996 Complies with Important Pathogenic Phenotypes
Achromobacter xylosoxidans is an environmental opportunistic pathogen, which infects an
increasing number of immunocompromised patients. In this study we combined genomic …
increasing number of immunocompromised patients. In this study we combined genomic …
[HTML][HTML] The Staphylococcus aureus ArlRS Two-Component System Is a Novel Regulator of Agglutination and Pathogenesis
JN Walker, HA Crosby, AR Spaulding… - PLoS …, 2013 - journals.plos.org
Staphylococcus aureus is a prominent bacterial pathogen that is known to agglutinate in the
presence of human plasma to form stable clumps. There is increasing evidence that …
presence of human plasma to form stable clumps. There is increasing evidence that …
[HTML][HTML] Antimicrobial Efficacy of Two Surface Barrier Discharges with Air Plasma against In Vitro Biofilms
R Matthes, C Bender, R Schlüter, I Koban, R Bussiahn… - PloS one, 2013 - journals.plos.org
The treatment of infected wounds is one possible therapeutic aspect of plasma medicine.
Chronic wounds are often associated with microbial biofilms which limit the efficacy of …
Chronic wounds are often associated with microbial biofilms which limit the efficacy of …