Polyprodrug amphiphiles: hierarchical assemblies for shape-regulated cellular internalization, trafficking, and drug delivery
Solution self-assembly of block copolymers (BCPs) typically generates spheres, rods, and
vesicles. The reproducible bottom-up fabrication of stable planar nanostructures remains …
vesicles. The reproducible bottom-up fabrication of stable planar nanostructures remains …
Synthetic approaches to RBC mimicry and oxygen carrier systems
CL Modery-Pawlowski, LL Tian, V Pan… - …, 2013 - ACS Publications
Whole blood or red blood cell (RBC) transfusions are highly significant, clinically, for blood
replacement therapies in traumatic injuries, presurgical conditions, and anemias. However …
replacement therapies in traumatic injuries, presurgical conditions, and anemias. However …
In vitro and in vivo hemostatic capabilities of a functionally integrated platelet-mimetic liposomal nanoconstruct
CL Modery-Pawlowski, LL Tian, M Ravikumar… - Biomaterials, 2013 - Elsevier
There is significant clinical interest in synthetic platelet substitutes that can mimic platelet's
hemostastic functionalities while allowing scale-up, minimal biological contamination, and …
hemostastic functionalities while allowing scale-up, minimal biological contamination, and …
A platelet-inspired paradigm for nanomedicine targeted to multiple diseases
CL Modery-Pawlowski, HH Kuo, WM Baldwin 3rd… - …, 2013 - Taylor & Francis
Platelets are megakaryocyte-derived anucleated cells found in the blood. They are mainly
responsible for rendering hemostasis or clotting to prevent bleeding complications …
responsible for rendering hemostasis or clotting to prevent bleeding complications …
Shear‐responsive platelet mimetics for targeted drug delivery
N Korin, M Kanapathipillai… - Israel Journal of …, 2013 - Wiley Online Library
Most targeted drug delivery approaches utilize molecular targets or regional variations in
chemical or structural properties of the tissue microenvironment to localize drug at disease …
chemical or structural properties of the tissue microenvironment to localize drug at disease …
[PDF][PDF] Nanoparticle biointerfacing via platelet membrane cloaking
Development of functional nanoparticles can be encumbered by unanticipated material
properties and biological events, which can negatively impact nanoparticle effectiveness in …
properties and biological events, which can negatively impact nanoparticle effectiveness in …