[HTML][HTML] Neural circuit mechanisms of post–traumatic epilepsy

RF Hunt, JA Boychuk, BN Smith - Frontiers in cellular neuroscience, 2013 - frontiersin.org
Traumatic brain injury (TBI) greatly increases the risk for a number of mental health
problems and is one of the most common causes of medically intractable epilepsy in …

[HTML][HTML] Brain injury, neuroinflammation and Alzheimer's disease

JJ Breunig, MV Guillot-Sestier, T Town - Frontiers in aging …, 2013 - frontiersin.org
With as many as 300,000 United States troops in Iraq and Afghanistan having suffered head
injuries (Miller,), traumatic brain injury (TBI) has garnered much recent attention. While the …

Traumatic brain injury induces macrophage subsets in the brain

CL Hsieh, CC Kim, BE Ryba, EC Niemi… - European journal of …, 2013 - Wiley Online Library
Traumatic brain injury (TBI) elicits innate inflammatory responses that can lead to secondary
brain injury. To better understand the mechanisms involved in TBI‐induced inflammation, we …

Inflammatory consequences in a rodent model of mild traumatic brain injury

JR Perez-Polo, HC Rea, KM Johnson… - Journal of …, 2013 - liebertpub.com
Mild traumatic brain injury (mTBI), particularly mild “blast type” injuries resulting from
improvised exploding devices and many sport-caused injuries to the brain, result in long …

Traumatic axonal injury in the mouse is accompanied by a dynamic inflammatory response, astroglial reactivity and complex behavioral changes

S Ekmark-Lewén, J Flygt, O Kiwanuka… - Journal of …, 2013 - Springer
Background Diffuse traumatic axonal injury (TAI), a common consequence of traumatic brain
injury, is associated with high morbidity and mortality. Inflammatory processes may play an …

Gene expression patterns following unilateral traumatic brain injury reveals a local pro-inflammatory and remote anti-inflammatory response

TE White, GD Ford, MC Surles-Zeigler, AS Gates… - BMC genomics, 2013 - Springer
Background Traumatic brain injury (TBI) results in irreversible damage at the site of impact
and initiates cellular and molecular processes that lead to secondary neural injury in the …

Decreased neuroinflammation and increased brain energy homeostasis following environmental enrichment after mild traumatic brain injury is associated with …

TL Briones, J Woods, M Rogozinska - Acta neuropathologica …, 2013 - Springer
Background Persistent neuroinflammation and disruptions in brain energy metabolism is
commonly seen in traumatic brain injury (TBI). Because of the lack of success of most TBI …

Analysis of functional pathways altered after mild traumatic brain injury

JB Redell, AN Moore, RJ Grill, D Johnson… - Journal of …, 2013 - liebertpub.com
Concussive injury (or mild traumatic brain injury; mTBI) can exhibit features of focal or diffuse
injury patterns. We compared and contrasted the cellular and molecular responses after mild …

Immediate splenectomy down-regulates the MAPK–NF-κB signaling pathway in rat brain after severe traumatic brain injury

W Chu, M Li, F Li, R Hu, Z Chen, J Lin… - Journal of Trauma and …, 2013 - journals.lww.com
BACKGROUND The treatment of severe traumatic brain injury (TBI) remains a difficult
process. One key to improving treatment efficacy is to reduce secondary brain injury. Local …

Plasticity of the contralateral motor cortex following focal traumatic brain injury in the rat

HW Axelson, T Winkler, J Flygt… - Restorative …, 2013 - content.iospress.com
Purpose: Recovery is limited following traumatic brain injury (TBI) since injured axons
regenerate poorly and replacement of lost cells is minimal. Behavioral improvements could …