Maintaining attention for more than a few seconds is essential for mastering everyday life.
Yet, our ability to stay focused on a particular task is limited, resulting in well-known …

The gap between symptoms and pathology in Alzheimer's disease has been explained by
the hypothetical construct of “cognitive reserve”—a set of variables including education …

The noradrenaline (norepinephrine) system exerts profound influences on cognition via
ascending projections to the forebrain, mostly originating from the locus coeruleus. This …

Rationale and objectives Modafinil (MOD) and its R-enantiomer (R-MOD) are approved
medications for narcolepsy and other sleep disorders. They have also been used, off-label …

Rationale Deficient response inhibition is a prominent feature of many pathological
conditions characterised by impulsive and compulsive behaviour. Clinically effective doses …

Executive dysfunction causes significant real-life disability for patients with spina bifida (SB).
However, no previous research has been directed toward the amelioration of executive …

Research has shown that extraverts performing a working memory task benefit more from
caffeine than do introverts. The present study aimed to replicate this and extend our …

Response inhibition, comprising action cancellation and action restraint, and error
awareness are executive functions of considerable clinical relevance to neuropsychiatric …

Pharmacological evidence suggests the importance of noradrenergic and other
monoaminergic neurotransmitters in the aetiology and treatment of attention deficit …

It has been repeatedly shown that functional magnetic resonance imaging (fMRI) triggers
distress and neuroendocrine response systems. Prior studies have revealed that …