The pathogenesis of many neurodegenerative disorders arises in association with the
misfolding and accumulation of a wide variety of proteins. Much emphasis has been placed …

Previous evidence indicates that a number of proteins are able to interact with cognate
mRNAs. These autogenous associations represent important regulatory mechanisms that …

Knowledge of the mechanisms of interaction between self-aggregating peptides and nucleic
acids or other polyanions is key to the understanding of many aggregation processes …

Anomalous protein aggregation is closely associated to age-related mental illness.
Extraneuronal plaques, mainly composed of aggregated amyloid peptides, are considered …

Non proteinaceous substances are found to be associated with toxic protein aggregates
commonly known as fibrils. Hen egg white lysozyme (HEWL) is able to form fibrillar species …

Aggregation, nuclear location, and nucleic acid interaction are common features shared by a
number of proteins related to neurodegenerative diseases, including Alzheimer's disease …

Amyloid-β peptide is presumably a key etiological factor involved in the pathogenesis of
Alzheimer's disease (AD), and several hypotheses exist on the possible ways Aβ contributes …

In various neurodegenerative diseases, including Alzheimer's disease, progressive
supranuclear palsy, Pick's disease, and corticobasal degeneration, the deposition of fibrils …

Until the end of the 1990s the data available and the genetics of the familial forms of amyloid
diseases supported a quite general consensus that the basic toxic species in amyloid …

Anions including nucleic acids and lipids have been found to promote amyloid formation in
diseases including neurodegenerative conditions such as Alzheimer's and Creutzfeldt …