Nanogel carrier design for targeted drug delivery
DM Eckmann, RJ Composto, A Tsourkas… - Journal of materials …, 2014 - pubs.rsc.org
Polymer-based nanogel formulations offer features attractive for drug delivery, including
ease of synthesis, controllable swelling and viscoelasticity as well as drug loading and …
ease of synthesis, controllable swelling and viscoelasticity as well as drug loading and …
[HTML][HTML] Different endocytotic uptake mechanisms for nanoparticles in epithelial cells and macrophages
DA Kuhn, D Vanhecke, B Michen… - Beilstein journal of …, 2014 - beilstein-journals.org
Precise knowledge regarding cellular uptake of nanoparticles is of great importance for
future biomedical applications. Four different endocytotic uptake mechanisms, that is …
future biomedical applications. Four different endocytotic uptake mechanisms, that is …
Rigid nanoparticle-based delivery of anti-cancer siRNA: challenges and opportunities
Gene therapy is a promising strategy to treat various genetic and acquired diseases. Small
interfering RNA (siRNA) is a revolutionary tool for gene therapy and the analysis of gene …
interfering RNA (siRNA) is a revolutionary tool for gene therapy and the analysis of gene …
Oral delivery of shRNA and siRNA via multifunctional polymeric nanoparticles for synergistic cancer therapy
L Han, C Tang, C Yin - Biomaterials, 2014 - Elsevier
Galactose modified trimethyl chitosan-cysteine (GTC) conjugates with various galactose
grafting densities were developed for oral delivery of Survivin shRNA-expression pDNA …
grafting densities were developed for oral delivery of Survivin shRNA-expression pDNA …
[PDF][PDF] Simultaneous Raman microspectroscopy and fluorescence imaging of bone mineralization in living zebrafish larvae
Confocal Raman microspectroscopy and fluorescence imaging are two well-established
methods providing functional insight into the extracellular matrix and into living cells and …
methods providing functional insight into the extracellular matrix and into living cells and …
NIR initiated and pH sensitive single-wall carbon nanotubes for doxorubicin intracellular delivery
In this work, we synthesized a pH sensitive poly (ethylene glycol)–doxorubicin (PEG–DOX)
on single-wall carbon nanotubes (SWNTs). Using multimodal nonlinear optical imaging …
on single-wall carbon nanotubes (SWNTs). Using multimodal nonlinear optical imaging …
Numerical simulations of in vitro nanoparticle toxicity–the case of poly (amido amine) dendrimers
A phenomenological rate equation model is constructed to numerically simulate
nanoparticle uptake and subsequent cellular response. Polyamidoamine dendrimers …
nanoparticle uptake and subsequent cellular response. Polyamidoamine dendrimers …
Bioavailability and bioaccumulation of metal-based engineered nanomaterials in aquatic environments: concepts and processes
Abstract Bioavailability of Me-ENMs to aquatic organisms links their release into the
environment to ecological implications. Close examination shows some important …
environment to ecological implications. Close examination shows some important …
Effects of cholesterol incorporation on the physicochemical, colloidal, and biological characteristics of pH-sensitive AB2 miktoarm polymer-based polymersomes
In our previous study, a histidine-based AB 2 miktoarm polymer, methoxy poly (ethylene
glycol)-b-poly (l-histidine) 2 (mPEG-b-(PolyHis) 2), was designed to construct pH-sensitive …
glycol)-b-poly (l-histidine) 2 (mPEG-b-(PolyHis) 2), was designed to construct pH-sensitive …
[HTML][HTML] Self-Assembled Micelles Composed of Doxorubicin Conjugated Y-Shaped PEG-Poly(glutamic acid)2 Copolymers via Hydrazone Linkers
In this work, micelles composed of doxorubicin-conjugated Y-shaped copolymers (YMs)
linked via an acid-labile linker were constructed. Y-shaped copolymers of mPEG-b-poly …
linked via an acid-labile linker were constructed. Y-shaped copolymers of mPEG-b-poly …