Severe or therapy-resistant asthma is increasingly recognised as a major unmet need. A
Task Force, supported by the European Respiratory Society and American Thoracic Society …

Background Airway inflammation is associated with asthma exacerbation risk, treatment
response, and disease mechanisms. Objective This study aimed to identify and validate a …

Increased airway smooth muscle (ASM) mass is a feature of asthmatic airways, and could
result from augmented proliferation. We determined whether proliferation and IL-6 release …

Chronic inflammation in the bronchi of long-term asthma patients worsens mood disorders,
which has been shown to correlate with elevated levels of multiple proinflammatory …

Recent genome-wide association studies (GWAs) have identified several new genetic risk
factors for asthma; however, their influence on disease behavior and treatment response is …

Objective—To investigate effects of intramammary administration of prednisolone on the
immune response of mammary glands in cows. Animals—5 lactating Red Holsteins …

Respiratory viral infections are associated with the majority of asthma attacks. Inhibitory M2
receptors on parasympathetic nerves, which normally limit acetylcholine (ACh) release, are …

Inspite of very safe and effective treatment, Bronchial asthmatics do not respond well in 5-
10% of cases which are labelled as Refractory Asthma. Besides compliance, presence of …

Despite the continuous increase in the prevalence of asthma in many developing countries,
there have been major advances in understanding and managing this disease. The …

BHR (angl. bronchial hyperresponsiveness)–bronchų hiperrektyvumas CCL2 (angl. CC
chemokine ligand 2)− CC chemokino ligandas 2 CCR (angl. CC chemokine receptor)− CC …