The dengue virus non-structural 1 protein: risks and benefits

JH Amorim, RP dos Santos Alves, SB Boscardin… - Virus research, 2014 - Elsevier
The dengue virus (DENV) non-structural 1 (NS1) protein plays a critical role in viral RNA
replication and has a central position in DENV pathogenesis. DENV NS1 is a glycoprotein …

Evaluation of commercially available diagnostic tests for the detection of dengue virus NS1 antigen and anti-dengue virus IgM antibody

EA Hunsperger, S Yoksan, P Buchy… - PLoS neglected …, 2014 - journals.plos.org
Commercially available diagnostic test kits for detection of dengue virus (DENV) non-
structural protein 1 (NS1) and anti-DENV IgM were evaluated for their sensitivity and …

Emergence of chikungunya fever on the French side of Saint Martin island, October to December 2013

S Cassadou, S Boucau, M Petit-Sinturel… - …, 2014 - eurosurveillance.org
On 18 November 2013, five residents of Saint Martin presented with severe joint pain after
an acute episode of dengue-like fever. Epidemiological, laboratory and entomological …

Dengue NS1 antigen as a marker of severe clinical disease

SA Paranavitane, L Gomes, A Kamaladasa… - BMC infectious …, 2014 - Springer
Background Early detection of complications significantly reduces dengue associated
mortality and morbidity. We set out to determine if the NS1 rapid antigen detection test could …

Rapid immunoglobulin M-based dengue diagnostic test using surface plasmon resonance biosensor

P Jahanshahi, E Zalnezhad, SD Sekaran… - Scientific reports, 2014 - nature.com
Surface plasmon resonance (SPR) is a medical diagnosis technique with high sensitivity
and specificity. In this research, a new method based on SPR is proposed for rapid, 10 …

Neurological manifestations of dengue viral infection

FJ Carod-Artal - Research and Reports in Tropical Medicine, 2014 - Taylor & Francis
Dengue is the most common mosquito-borne viral infection worldwide. There is increased
evidence for dengue virus neurotropism, and neurological manifestations could make part of …

[HTML][HTML] NS1-based tests with diagnostic utility for confirming dengue infection: a meta-analysis

H Zhang, W Li, J Wang, H Peng, X Che, X Chen… - International Journal of …, 2014 - Elsevier
Objectives Non-structural protein 1 (NS1)-based tests may offer a larger window of
opportunity for dengue diagnosis and could constitute a very useful diagnostic tool. The aim …

Evaluation of a dengue NS1 antigen detection assay sensitivity and specificity for the diagnosis of acute dengue virus infection

LL Hermann, B Thaisomboonsuk… - PLoS neglected …, 2014 - journals.plos.org
Background Currently, no dengue NS1 detection kit has regulatory approval for the
diagnosis of acute dengue fever. Here we report the sensitivity and specificity of the InBios …

Assessing positivity and circulating levels of NS1 in samples from a 2012 dengue outbreak in Rio de Janeiro, Brazil

D Allonso, MDF Meneses, CA Fernandes, DF Ferreira… - PLoS …, 2014 - journals.plos.org
Dengue virus (DENV) represents a major threat to public health worldwide. Early DENV
diagnosis should not only detect the infection but also identify patients with a higher …

A meta-analysis of the diagnostic accuracy of two commercial NS1 antigen ELISA tests for early dengue virus detection

VG Costa, AC Marques-Silva, ML Moreli - PLoS One, 2014 - journals.plos.org
Background Dengue virus (DENV) NS1 antigen detection is regarded as an early diagnostic
marker. Accordingly, several studies have evaluated the performance of tests that utilize …