Y-box binding protein 1–a prognostic marker and target in tumour therapy

C Kosnopfel, T Sinnberg, B Schittek - European journal of cell biology, 2014 - Elsevier
Y-box binding protein 1 (YB-1) is a multifunctional protein involved in various cellular
processes including both transcriptional and translational regulation of target gene …

The role of cold shock domain proteins in inflammatory diseases

JA Lindquist, S Brandt, A Bernhardt, C Zhu… - Journal of molecular …, 2014 - Springer
Cold shock domain proteins are characterized by the presence of one or more evolutionarily
conserved cold shock domains, which each possess two nucleic acid-binding motifs. These …

[HTML][HTML] Identification of fatty acid binding protein 4 as an adipokine that regulates insulin secretion during obesity

LE Wu, D Samocha-Bonet, PT Whitworth… - Molecular …, 2014 - Elsevier
A critical feature of obesity is enhanced insulin secretion from pancreatic β-cells, enabling
the majority of individuals to maintain glycaemic control despite adiposity and insulin …

Rapid temporal dynamics of transcription, protein synthesis, and secretion during macrophage activation

K Eichelbaum, J Krijgsveld - Molecular & Cellular Proteomics, 2014 - ASBMB
Macrophages provide the first line of host defense with their capacity to react to an array of
cytokines and bacterial components requiring tight regulation of protein expression and …

Differential control of interleukin-6 mRNA levels by cellular distribution of YB-1

S Kang, TA Lee, EA Ra, E Lee, HJ Choi, S Lee… - PLoS One, 2014 - journals.plos.org
Cytokine production is essential for innate and adaptive immunity against microbial invaders
and must be tightly controlled. Cytokine messenger RNA (mRNA) is in constant flux between …

Roles of YB-1 under arsenite-induced stress: translational activation of HSP70 mRNA and control of the number of stress granules

T Tanaka, S Ohashi, S Kobayashi - Biochimica et Biophysica Acta (BBA) …, 2014 - Elsevier
Background When cells become stressed, they form stress granules (SGs) and show an
increase of the molecular chaperone HSP70. The translational regulator YB-1 is a …

High prevalence of Y-box protein-1/p18 fragment in plasma of patients with malignancies of different origin

F Tacke, O Galm, N Kanig, E Yagmur, S Brandt… - BMC cancer, 2014 - Springer
Background Expression of the cold shock protein Y-box protein 1 (YB-1) is associated with
deleterious outcome in various malignant diseases. Our group recently showed that the …

Molecular signatures that correlate with induction of lens regeneration in newts: lessons from proteomic analysis

K Sousounis, R Bhavsar, M Looso, M Krüger, J Beebe… - Human Genomics, 2014 - Springer
Background Amphibians have the remarkable ability to regenerate missing body parts. After
complete removal of the eye lens, the dorsal but not the ventral iris will transdifferentiate to …

Некоторые новые аспекты исследований множественной лекарственной устойчивости опухолевых клеток

АА Ставровская, ГП Генс - Успехи молекулярной онкологии, 2014 - cyberleninka.ru
Множественная лекарственная устойчивость (МЛУ) опухолевых клеток резистентность
клетки одновременно к большому количеству веществ, разных по химическому …

Evaluation of the Schistosoma mansoni Y-box-binding protein (SMYB1) potential as a vaccine candidate against schistosomiasis

SRC Dias, M Boroni, EA Rocha, TL Dias… - Frontiers in …, 2014 - frontiersin.org
Schistosomiasis is a neglected tropical disease, and after malaria, is the second most
important tropical disease in public health. A vaccine that reduces parasitemia is desirable …