There is a continuous need for iterative cycles of antibiotic discovery and development to
deal with the selection of resistant pathogens that emerge as therapeutic application of an …

As the key components of innate immunity, human host defense antimicrobial peptides and
proteins (AMPs) play a critical role in warding off invading microbial pathogens. In addition …

Short antimicrobial peptides rich in arginine (R) and tryptophan (W) interact with
membranes. To learn how this interaction leads to bacterial death, we characterized the …

The pulmonary airways are continuously exposed to bacteria. As a first line of defense
against infection, the airway surface liquid (ASL) contains a complex mixture of antimicrobial …

Fungi and bacteria compete with an arsenal of secreted molecules for their ecological niche.
This repertoire represents a rich and inexhaustible source for antibiotics and fungicides …

Cationic antimicrobial peptides (CAPs) such as defensins are ubiquitously found innate
immune molecules that often exhibit broad activity against microbial pathogens and …

Over the last years, antimicrobial peptides (AMPs) have been the focus of intense research
toward the finding of a viable alternative to current antifungal drugs. Defensins are one of the …

Antimicrobial peptides, or AMPs, play a significant role in many environments as a tool to
remove competing organisms. In response, many bacteria have evolved mechanisms to …

A novel bacteriocin, plantaricin ZJ008 produced by Lactobacillus plantarum ZJ008 isolated
from fresh milk, was purified by XAD 2, cation exchange chromatograph, gel chromatograph …

The peptidoglycan is the structural polymer of the bacterial cell envelope. In contrast to an
expectation of a structural stasis for this polymer, during the growth of the Gram-negative …