DNA condensation induced by metal complexes

GY Li, RL Guan, LN Ji, H Chao - Coordination Chemistry Reviews, 2014 - Elsevier
DNA is stored in a highly compact, condensed phase in viruses, bacteria and eukaryotes.
Co (NH 3) 6 3+ is a well-known inorganic cation that can induce DNA condensation, and …

Interaction of G-quadruplexes in the full-length 3′ human telomeric overhang

J Abraham Punnoose, Y Cui, D Koirala… - Journal of the …, 2014 - ACS Publications
The 3′ human telomeric overhang provides ample opportunities for the formation and
interaction of G-quadruplexes, which have shown impacts on many biological functions …

Ultrasensitive telomerase activity detection in circulating tumor cells based on DNA metallization and sharp solid‐state electrochemical techniques

L Wu, J Wang, J Ren, X Qu - Advanced Functional Materials, 2014 - Wiley Online Library
Being considered a “liquid biopsy”, circulating tumor cell (CTC) quantification is of great
interest for evaluating cancer dissemination, predicting patient prognosis, and also for the …

Recognition of Nucleic Acid Junctions Using Triptycene‐Based Molecules

SA Barros, DM Chenoweth - Angewandte Chemie International …, 2014 - Wiley Online Library
The modulation of nucleic acids by small molecules is an essential process across the
kingdoms of life. Targeting nucleic acids with small molecules represents a significant …

Exo- and endo-hedral interactions of counteranions with tetracationic Pd2L4 metallosupramolecular architectures

JEM Lewis, JD Crowley - Supramolecular Chemistry, 2014 - Taylor & Francis
A series of [Pd2L4] 4+(X−) 4 metallosupramolecular architectures have been synthesised
where X−=,, OTf−, OMs− or OTs− and L= 2, 6-bis (pyridin-3-ylethynyl) pyridine. These …

G-Quadruplex binding enantiomers show chiral selective interactions with human telomere

J Wang, Y Chen, J Ren, C Zhao, X Qu - Nucleic acids research, 2014 - academic.oup.com
Chiral recognition of DNA molecules is important because DNA chiral transition and its
different conformations are involved in a series of important life events. Among them …

Artificial evolution of graphene oxide chemzyme with enantioselectivity and near‐infrared photothermal effect for cascade biocatalysis reactions

C Xu, C Zhao, M Li, L Wu, J Ren, X Qu - Small, 2014 - Wiley Online Library
It is highly desirable and challenging when the chemzyme can be not only simply
duplicating and imitating the properties of natural enzymes, but also introducing additional …

Recognition of DNA bulges by dinuclear iron (II) metallosupramolecular helicates

J Malina, MJ Hannon, V Brabec - The FEBS Journal, 2014 - Wiley Online Library
Bulged DNA structures are of general biological significance because of their important
roles in a number of biochemical processes. Compounds capable of targeting bulged DNA …

Using ancillary ligands to tune the DNA binding properties of self-assembled luminescent metallomacrocycles

H Ahmad, D Ghosh, JA Thomas - Chemical Communications, 2014 - pubs.rsc.org
Using ancillary ligands to tune the DNA binding properties of self-assembled luminescent
metallomacrocycles - Chemical Communications (RSC Publishing) DOI:10.1039/C4CC00997E …

Design and synthesis of a new dimeric xanthone derivative: enhancement of G-quadruplex selectivity and telomere damage

M Franceschin, D Nocioni, A Biroccio… - Organic & …, 2014 - pubs.rsc.org
Following the results we previously reported on a series of xanthene and xanthone
derivatives as G-quadruplex stabilizing ligands, in order to obtain a more selective …