[HTML][HTML] PML tumour suppression and beyond: therapeutic implications
Recognition of the tumour suppressive capacity of the Promyelocytic Leukemia protein
(PML) has emerged beyond its identification through APL, to a broad spectrum of tumors …
(PML) has emerged beyond its identification through APL, to a broad spectrum of tumors …
Dynamics of leukemia stem-like cell extinction in acute promyelocytic leukemia
B Werner, RE Gallagher, EM Paietta, MR Litzow… - Cancer research, 2014 - AACR
Many tumors are believed to be maintained by a small number of cancer stem–like cells,
where cure is thought to require eradication of this cell population. In this study, we …
where cure is thought to require eradication of this cell population. In this study, we …
FRAP 技术揭示PLZF-RARα 融合蛋白在细胞核内的运动性依赖于其配基及转录活性
贺薇， 黄莺 - 上海交通大学学报: 医学版, 2014 - cqvip.com
目的运用光漂白荧光恢复(FRAP) 技术检测一系列带有绿色荧光蛋白(GFP)
标签的野生型及突变型的早幼粒细胞性白血病锌指-维甲酸受体α (PLZF-RARα) …
标签的野生型及突变型的早幼粒细胞性白血病锌指-维甲酸受体α (PLZF-RARα) …
Role of the histone demethylase LSD1 in the regulation of differentiation of acute promyelocytic leukemia cells
PL Rossi - 2014 - air.unimi.it
Acute promyelocytic leukemia (APL) is characterized by the appearance of blasts,
insensitive to physiological retinoic acid (RA)-dependent differentiation and in the majority of …
insensitive to physiological retinoic acid (RA)-dependent differentiation and in the majority of …
Application of novel genotyping microarray technologies in cancer research
R Ramos, J Moreno-Rubio, E Casado… - Comprehensive …, 2014 - Elsevier
Cancer is a genetic disease. The impact of genetic alterations of tumor cells on cancer
patient prognosis and treatment has been extensively demonstrated in the past decades. In …
patient prognosis and treatment has been extensively demonstrated in the past decades. In …