The effect of a geriatric evaluation on treatment decisions for older cancer patients–a systematic review

ME Hamaker, AH Schiphorst… - Acta …, 2014 - Taylor & Francis
Aim. The aim of this systematic review is to summarise all available data on the effect of a
geriatric evaluation on the multidisciplinary treatment of older cancer patients, focussing on …

Participation of the elderly population in clinical trials: barriers and solutions

AC Denson, A Mahipal - Cancer Control, 2014 - journals.sagepub.com
Background Despite the fact that cancer disproportionately affects the elderly, most
participants of clinical cancer trials are relatively young. This misrepresentation greatly …

Randomised controlled trials and population-based observational research: partners in the evolution of medical evidence

CM Booth, IF Tannock - British journal of cancer, 2014 - nature.com
Recent reports have highlighted the distinct roles and occasional tension between
randomised controlled trials (RCTs) and population-based observational research (Concato …

Age-specific changes in intrinsic breast cancer subtypes: a focus on older women

EO Jenkins, AM Deal, CK Anders, A Prat… - The …, 2014 - academic.oup.com
Purpose. Breast cancer (BC) is a disease of aging and the number of older BC patients in
the US is rising. Immunohistochemical data show that with increasing age, the incidence of …

Cancer treatment disparities in HIV-infected individuals in the United States

G Suneja, MS Shiels, R Angulo… - Journal of Clinical …, 2014 - ascopubs.org
Purpose HIV-infected individuals with cancer have worse survival rates compared with their
HIV-uninfected counterparts. One explanation may be differing cancer treatment; however …

Exclusion of older patients from ongoing clinical trials for hematological malignancies: an evaluation of the National Institutes of Health Clinical Trial Registry

ME Hamaker, R Stauder, BC van Munster - The oncologist, 2014 - academic.oup.com
Introduction. Cancer societies, research cooperatives, and countless publications have
urged the development of clinical trials that facilitate the inclusion of older patients and those …

External validity of a trial comprised of elderly patients with hormone receptor–positive breast cancer

W van de Water, M Kiderlen… - Journal of the …, 2014 - academic.oup.com
Background Inclusion in trials is selective, and thus results may not be generalizable to the
general population. The aim of this study was to investigate the external validity of …

Impact of robotics on the outcome of elderly patients with endometrial cancer

V Lavoue, X Zeng, S Lau, JZ Press, J Abitbol… - Gynecologic …, 2014 - Elsevier
Objective To evaluate the impact of introducing a robotics program on clinical outcome of
elderly patients with endometrial cancer. Methods Evaluation and comparison of peri …

Efficacy and safety of sunitinib in elderly patients with metastatic renal cell carcinoma

TE Hutson, RM Bukowski, BI Rini, ME Gore… - British journal of …, 2014 - nature.com
Background: We retrospectively analyzed sunitinib outcome as a function of age in
metastatic renal cell carcinoma (mRCC) patients. Methods: Data were pooled from 1059 …

[HTML][HTML] Cancer economics, policy and politics: what informs the debate? Perspectives from the EU, Canada and US

A Aggarwal, O Ginsburg, T Fojo - Journal of Cancer Policy, 2014 - Elsevier
In high-income countries the public policy consensus is that costs of delivering high-quality
equitable cancer care present an increasing challenge to national budgets. In the US alone …