Although the gastrointestinal (GI) tract possesses intrinsic neural plexuses that allow a
significant degree of autonomy over GI functions, the central nervous system (CNS) provides …

The neuroendocrine system governs essential survival and homeostatic functions. For
example, growth is needed for development, thermoregulation maintains optimal core …

Monogenic diabetes represents a heterogeneous group of disorders resulting from defects
in single genes. Defects are categorized primarily into two groups: disruption of β‐cell …

Food intake in fish is a complex process regulated through many different factors including
abundance of energy and nutrients. In recent years, evidence have been obtained in several …

It is increasingly apparent that the brain plays a central role in metabolic homeostasis,
including the maintenance of blood glucose. This is achieved by various efferent pathways …

The carotid body (CB) is a key chemoreceptor organ in which glomus cells sense changes
in blood O2, CO2, and pH levels. CB glomus cells have also been found to detect …

Introduction: Glucokinase (GK) is a key regulator of glucose homeostasis, and development
of small molecule activators of this enzyme represents a promising new approach for the …

Glucoprivation activates neurons in the perifornical hypothalamus (PeH) and in the rostral
ventrolateral medulla (RVLM), which results in the release of adrenaline. The current study …

Insulin‐induced hypoglycaemia (IIH) is a major acute complication in type 1 as well as in
type 2 diabetes, particularly during intensive insulin therapy. The brain plays a central role in …

Glucokinase (GK), the hexokinase involved in glucose sensing in pancreatic β cells, is also
expressed in hypothalamic tanycytes, which cover the ventricular walls of the basal …