Seasonal increases in peripheral innate lymphoid type 2 cells are inhibited by subcutaneous grass pollen immunotherapy

M Lao-Araya, E Steveling, GW Scadding… - Journal of Allergy and …, 2014 - jacionline.org
To the Editor: We report for the first time the effects of grass pollen subcutaneous
immunotherapy (SCIT) on the novel subset of innate lymphoid type 2 cells (ILC2s) in …

Immunotherapy for house dust mite sensitivity: where are the knowledge gaps?

M Biagtan, R Viswanathan, RK Bush - Current allergy and asthma reports, 2014 - Springer
House dust mites (HDMs) are found in the environments where human habitation exists.
Their density is dependent on environmental relative humidity; therefore, higher populations …

Oral immunotherapy for treatment of immunoglobulin E-mediated food allergy: the transition to clinical practice

GB Pajno, L Cox, L Caminiti, V Ramistella… - Pediatric Allergy …, 2014 - liebertpub.com
Today, there is neither an effective nor an active treatment for food allergy. Allergy
immunotherapy has been proposed as an attractive strategy to actively treat food allergy …

Immunological comparison of allergen immunotherapy tablet treatment and subcutaneous immunotherapy against grass allergy

K Aasbjerg, V Backer, G Lund, J Holm… - Clinical & …, 2014 - Wiley Online Library
Background IgE‐mediated allergic rhinitis to grass pollen can successfully be treated with
either allergen immunotherapy tablets (SLIT tablet) or SQ‐standardized subcutaneous …

The regulatory T cells induction by epicutaneous immunotherapy is sustained and mediates long‐term protection from eosinophilic disorders in peanut‐sensitized …

V Dioszeghy, L Mondoulet, V Dhelft… - Clinical & …, 2014 - Wiley Online Library
Background Allergen‐specific immunotherapy favours immune deviation from a Th2 to a
Th1 response and increases the number of regulatory T cells (Tregs). Epicutaneous …

Preventive sublingual immunotherapy in preschool children: first evidence for safety and pro‐tolerogenic effects

Z Szépfalusi, C Bannert, L Ronceray… - Pediatric Allergy and …, 2014 - Wiley Online Library
Abstract Background Prevention of new IgE sensitizations has been described during
allergen‐specific immunotherapy. However, prospective data using a preventive approach …

A high polymerized grass pollen extract is efficacious and safe in a randomized double‐blind, placebo‐controlled study using a novel up‐dosing cluster‐protocol

L Klimek, J Uhlig, R Mösges, K Rettig, O Pfaar - Allergy, 2014 - Wiley Online Library
Background Cluster immunotherapy represents an interesting alternative to conventional up‐
dosing schedules because it allows achieving the maintenance dose within a shorter time …

The use of single versus multiple antigens in specific allergen immunotherapy for allergic rhinitis: review of the evidence

G Passalacqua - Current Opinion in Allergy and Clinical …, 2014 - journals.lww.com
The evidence for the efficacy of allergen mixes is still weak, but component-resolved
diagnosis could represent a valuable help in selecting the allergen. As a matter of fact …

Prenatal phthalate and early childhood bisphenol A exposures increase asthma risk in inner-city children

RM Whyatt, AG Rundle, MS Perzanowski… - Journal of Allergy and …, 2014 - jacionline.org
6. Chang JE, Doherty TA, Baum R, Broide D. Prostaglandin D2 regulates human type 2
innate lymphoid cell chemotaxis. J Allergy Clin Immunol 2014; 133: 899-901. e3. 7. Doherty …

Advances in synthetic peptide immuno-regulatory epitopes

PS Creticos - World Allergy Organization Journal, 2014 - Springer
Synthetic peptide immuno-regulatory epitopes (SPIRE) represent a new class of
therapeutics for allergen immunotherapy that offer the potential to suppress the IgE …