Exploiting DNA mismatch repair deficiency as a therapeutic strategy

D Guillotin, SA Martin - Experimental cell research, 2014 - Elsevier
Abstract The DNA Mismatch repair (MMR) pathway is critical for the maintenance of genomic
stability. It is primarily responsible for the recognition and repair of mismatches that occur …

[HTML][HTML] Иммуногистохимическое исследование MSH2, PMS2, MLH1, MSH6 в сопоставлении с анализом микросателлитной нестабильности в …

ГА Раскин, ГА Янус, АВ Корнилов, РВ Орлова… - Вопросы …, 2014 - cyberleninka.ru
Аденокарцинома толстой кишки, по данным литературы, в 10-20% случаев связана с
микросателлитной нестабильностью, которая может наблюдаться как в спорадических …

Novel insights into MACC1 transcriptional regulation for identifying small molecule MACC1 inhibitors to restrict colorectal cancer progression

M Juneja - 2014 - edoc.hu-berlin.de
MACC1 has been reported as a prognostic biomarker for tumor progression and metastasis-
free survival in CRC along with other solid tumors. It induces cell motility and proliferation in …

[PDF][PDF] Biochemical Effects of Inherited MMR Gene Mutations and Diet on Colon Cancer Risk

DĐ BEBEK - helda.helsinki.fi
Colorectal cancer (CRC) is one of the leading causes of death in developed countries.
Although, a small fraction of cancers are caused by inherited genetic predisposition most of …

[PDF][PDF] Detecting de novo microsatellite mutations in a population of families with sporadic autism

M Bekritsky - 2014 - repository.cshl.edu
ADDM Autism and Developmental Disabilities Monitoring AGRE Autism Genetic Resource
Exchange AIB1 amplified in breast cancer 1, also known as NCOA3, or nuclear receptor …

Význam repetitivních sekvencí v lékařské a forenzní genetice

E Cerovská - 2014 - dspace.cuni.cz
Repetitivní sekvence jsou důležité pro genom i pro celý organismus. Tyto nekódující
sekvence tvoří velkou část genomu a říká se jim" odpadní DNA". V mnoha odvětvích vědy …

Cáncer colorectal e inestabilidad genómica: asociación con la pérdida de HLA y con el patrón de infiltración inflamatroria tumoral

M Bernal Sánchez - 2014 - digibug.ugr.es
La doctoranda Mónica Bernal Sánchez y los directores de la tesis Francisco Ruíz-Cabello
Osuna, Federico Garrido Torres-Puchol y Ángel Concha López, garantizamos, al firmar esta …

[引用][C] 胰岛素样生长因子2 受体基因3'非翻译区的单核苷酸多态性及其生物信息学分析

陈凤霞, 张文文, 杨芳, 管晓翔 - 医学研究生学报, 2014