The Complexity and Diversity of the Pathogenicity Locus in Clostridium difficile Clade 5

B Elliott, KE Dingle, X Didelot… - Genome biology and …, 2014 - academic.oup.com
The symptoms of Clostridium difficile infection are caused by two closely related toxins, TcdA
and TcdB, which are encoded by the 19.6 kb Pathogenicity Locus (PaLoc). The PaLoc is …

The impact of horizontal gene transfer on the biology of Clostridium difficile

AP Roberts, E Allan, P Mullany - Advances in microbial physiology, 2014 - Elsevier
Clostridium difficile infection (CDI) is now recognised as the main cause of healthcare
associated diarrhoea. Over the recent years there has been a change in the epidemiology of …

Intracellular Transport Mechanisms in Clostridium difficile, a Human Pathogen

MP Garver, H Yu, S Liu - Journal of Bioprocess Engineering …, 2014 - ingentaconnect.com
Clostridium difficile is the leading cause of nosocomial diarrhea and one of the most
common and costly hospital acquired infections. It is increasingly resistant to antibiotic …