Paracetamol is one of the most prescribed drugs globally, due to its antipyretic and
analgesic properties. However, it is highly toxic at elevated doses, with involvement of an …

Drug-induced hepatotoxicity is a significant cause of acute liver failure and is usually the
primary reason that therapeutic drugs are removed from the commercial market. Multiple …

Context: Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most commonly
used pharmaceuticals in Mexico, but there is not proper regulation on the sale, use and …

Acetaminophen (APAP) overdose causes severe hepatotoxicity in animals and humans.
However, the mechanisms underlying the gender differences in susceptibility to APAP …

Acetylsalicylic acid is a nonsteroidal anti-inflammatory widely used due to its low cost and
high effectiveness. This compound has been found in water bodies worldwide and is toxic to …

In the present study, we investigated the hepatoprotective potential of Parinari curatellifolia
Planch (Chrysobalanaceae) in experimental rats in order to ascertain the validity of folkloric …

The Asian clam Corbicula fluminea is an invasive bivalve that has recently spread in Europe
and currently represents a large portion of the aquatic biomass in specific areas. Because of …

Acetaminophen is globally one of the most prescribed drugs due to its antipyretic and
analgesic properties. However, it is highly toxic when the dosage surpasses the …

Oxidative stress is critically involved in a variety of diseases. Reactive oxygen species (ROS)
are highly toxic molecules that are generated during the body′ s metabolic reactions and …

Toxicity in natural ecosystems is usually not due to exposure to a single substance, but is
rather the result of exposure to mixtures of toxic substances. Knowing the effects of …