Innate immunity to adenovirus
R Hendrickx, N Stichling, J Koelen, L Kuryk… - Human gene …, 2014 - liebertpub.com
Human adenoviruses are the most widely used vectors in gene medicine, with applications
ranging from oncolytic therapies to vaccinations, but adenovirus vectors are not without side …
ranging from oncolytic therapies to vaccinations, but adenovirus vectors are not without side …
[HTML][HTML] Structure, function and dynamics in adenovirus maturation
WF Mangel, C San Martín - Viruses, 2014 - mdpi.com
Here we review the current knowledge on maturation of adenovirus, a non-enveloped
icosahedral eukaryotic virus. The adenovirus dsDNA genome fills the capsid in complex with …
icosahedral eukaryotic virus. The adenovirus dsDNA genome fills the capsid in complex with …
[HTML][HTML] Quantitative microscopy of functional HIV post-entry complexes reveals association of replication with the viral capsid
The steps from HIV-1 cytoplasmic entry until integration of the reverse transcribed genome
are currently enigmatic. They occur in ill-defined reverse-transcription-and pre-integration …
are currently enigmatic. They occur in ill-defined reverse-transcription-and pre-integration …
Alkene–tetrazine ligation for imaging cellular DNA
U Rieder, NW Luedtke - Angewandte Chemie International …, 2014 - Wiley Online Library
Vinyl‐2′‐deoxyuridine (VdU) is the first reported metabolic probe for cellular DNA
synthesis that can be visualized by using an inverse electron demand Diels–Alder reaction …
synthesis that can be visualized by using an inverse electron demand Diels–Alder reaction …
An azide‐modified nucleoside for metabolic labeling of DNA
AB Neef, NW Luedtke - ChemBioChem, 2014 - Wiley Online Library
Metabolic incorporation of azido nucleoside analogues into living cells can enable sensitive
detection of DNA replication through copper (I)‐catalyzed azide–alkyne cycloaddition …
detection of DNA replication through copper (I)‐catalyzed azide–alkyne cycloaddition …
[HTML][HTML] siRNA screen of early poxvirus genes identifies the AAA+ ATPase D5 as the virus genome-uncoating factor
S Kilcher, FI Schmidt, C Schneider, M Kopf… - Cell host & …, 2014 - cell.com
Poxvirus genome uncoating is a two-step process. First, cytoplasmic viral cores are activated
and early viral genes are expressed. Next, cores are disassembled and the genomes …
and early viral genes are expressed. Next, cores are disassembled and the genomes …
Chemical induction of unfolded protein response enhances cancer cell killing through lytic virus infection
V Prasad, M Suomalainen, M Pennauer… - Journal of …, 2014 - Am Soc Microbiol
Cancer cells are susceptible to oncolytic viruses, albeit variably. Human adenoviruses
(HAdVs) are widely used oncolytic agents that have been engineered to produce progeny …
(HAdVs) are widely used oncolytic agents that have been engineered to produce progeny …
[HTML][HTML] Superresolution imaging of human cytomegalovirus vMIA localization in sub-mitochondrial compartments
S Bhuvanendran, K Salka, K Rainey, SC Sreetama… - Viruses, 2014 - mdpi.com
The human cytomegalovirus (HCMV) viral mitochondria-localized inhibitor of apoptosis
(vMIA) protein, traffics to mitochondria-associated membranes (MAM), where the …
(vMIA) protein, traffics to mitochondria-associated membranes (MAM), where the …
[HTML][HTML] How cells tune viral mechanics—insights from biophysical measurements of influenza virus
UF Greber - Biophysical journal, 2014 - cell.com
During replication, the physical state of a virus is controlled by assembly and disassembly
processes, when particles are put together and dismantled by cellular cues, respectively. A …
processes, when particles are put together and dismantled by cellular cues, respectively. A …
Analysis of purified wild type and mutant adenovirus particles by SILAC based quantitative proteomics
A Alqahtani, K Heesom, JL Bramson… - Journal of General …, 2014 - microbiologyresearch.org
We used SILAC (stable isotope labelling of amino acids in cell culture) and high-throughput
quantitative MS mass spectrometry to analyse the protein composition of highly purified WT …
quantitative MS mass spectrometry to analyse the protein composition of highly purified WT …