Recent in vivo evidences of particle-based delivery of small-interfering RNA (siRNA) into solid tumors
Y Wen, WS Meng - Journal of pharmaceutical innovation, 2014 - Springer
Small-interfering RNA (siRNA) is both a powerful tool in research and a promising
therapeutic platform to modulate expression of disease-related genes. Malignant tumors are …
therapeutic platform to modulate expression of disease-related genes. Malignant tumors are …
Removal of total organic carbon from sewage wastewater using poly (ethylenimine)-functionalized magnetic nanoparticles
R Lakshmanan, M Sanchez-Dominguez… - Langmuir, 2014 - ACS Publications
The increased levels of organic carbon in sewage wastewater during recent years impose a
great challenge to the existing wastewater treatment process (WWTP). Technological …
great challenge to the existing wastewater treatment process (WWTP). Technological …
High gene delivery efficiency of alkylated low-molecular-weight polyethylenimine through gemini surfactant-like effect
S Liu, W Huang, MJ Jin, QM Wang… - International Journal …, 2014 - Taylor & Francis
To our knowledge, the mechanism underlying the high transfection efficiency of alkylated
low-molecular-weight polyethylenimine (PEI) is not yet well understood. In this work, we …
low-molecular-weight polyethylenimine (PEI) is not yet well understood. In this work, we …
Self-Assembled Gold Nanoplexes for Cancer-Targeted SiRNA Delivery
Y Shi - 2014 - aquila.usm.edu
Through layer-by-layer method, the authors have constructed three Au nanoplexes:
AuPEI/RNA/PEI, AuPEI/RNA/PEI-mPEG, and AuPEI/NA/PEI-PEG-FA. All the nanoplexes are …
AuPEI/RNA/PEI, AuPEI/RNA/PEI-mPEG, and AuPEI/NA/PEI-PEG-FA. All the nanoplexes are …
Using RNAi screening technologies to interrogate the extrinsic apoptosis pathway
JP Stephan - Methods in Enzymology, 2014 - Elsevier
Despite the knowledge accumulated during the last two decades about programmed cell
death, further investigations of the complex regulatory network of apoptosis, including the …
death, further investigations of the complex regulatory network of apoptosis, including the …
Application of Polyethylenimine-Based Nanoparticles for RNA Therapeutics
RNA interference is a post-transcriptional gene silencing mechanism mediated by double-
stranded small interfering RNA (siRNA). The application of siRNA as a therapeutic modality …
stranded small interfering RNA (siRNA). The application of siRNA as a therapeutic modality …