Pulmonary arterial hypertension (PAH) is a devastating and progressive disease with
marked morbidity and mortality. Even though being female represents one of the most …

Animal models of cancer have been instrumental in advancing our understanding of the
biology of tumor initiation and progression, in studying gene function and in performing …

Objective: To update practice guidelines for the therapeutic use of androgens in women.
Participants: A Task Force appointed by the Endocrine Society, American Congress of …

Background Increased levels of thyroglobulin (Tg) and thyroid-stimulating hormone (TSH)
are associated with differentiated thyroid carcinoma (TC) risk, but strong epidemiological …

Introduction In trans women (male-to-female transsexual persons), cross-sex hormone
therapy is administered to induce feminization. Breast development is an important part of …

The Hippo signaling pathway has been implicated as a conserved regulator of organ size in
both Drosophila and mammals. Yes-associated protein (YAP), the central component of the …

Results from prospective studies on premenopausal serum hormone levels in relation to
breast cancer risk have been inconclusive, especially with regard to tumor subtypes. Using a …

Observational and randomized controlled trial data have extensively examined the
relationship between menopausal hormone therapy (MHT) and risk of developing breast …

Purpose Endogenous hormones are risk factors for postmenopausal breast cancer, and
their measurement may improve our ability to identify high-risk women. Therefore, we …

Experimental evidence shows cross‐talk in mammary cells between estrogen, insulin‐like
growth factor I (IGF‐I) and their respective receptors and possible synergistic effects of …